水生呼肠孤病毒基因组研究进展  

Progress on Aquareovirus Genome

作　　者：殷亮[1,2] 王庆[1] 曾伟伟[1] 李永刚[1,2] 王英英[1] 石存斌[1] 吴淑勤[1] 

机构地区：[1]中国水产科学研究院珠江水产研究所农业部渔药创制重点实验室,广东广州510380 [2]上海海洋大学水产与生命学院,上海201306

出　　处：《动物医学进展》2013年第1期80-85,共6页Progress In Veterinary Medicine

基　　金：现代产业技术体系建设专项资金项目(CARS-46);国家自然科学基金项目(31202026);中国水产科学研究院基本科研业务费项目(2012A0506)

摘　　要：水生呼肠孤病毒隶属于呼肠孤病毒科水生呼肠孤病毒属,可感染多种淡水或海水水生动物并造成不同程度危害,严重影响了水产养殖业健康发展。水生呼肠孤病毒基因组为分11个节段的双链RNA,推测编码12种结构多肽。论文综述了近年来水生呼肠孤病毒基因组序列测定及其应用的研究进展,为进一步了解水生呼肠孤病毒基因组的多样性,推测其编码蛋白的功能及检测方法的建立,基因工程疫苗的研制,以及抗病毒研究提供借鉴和参考。Aquareovirus belongs to genus Aquareovirus in the family Reoviridae. It can infect a wide variety of aquatic animals resulted in different degree damage, which bring to significant threat to aquacultural in- dustrythroughout the world. The common genome of aquareovirus is composed of 11 segments of double- stranded RNA （dsRNA） and encoded putative 12 proteins. This article summarized the research progress on determination of aquareovirus genome and its application, offering more data about the diversity of aquareovirus genome, the function of the encoded proteins and also scientific basis for the establishment of detection method, development of genetic engineering vaccine and antiviral research.

关 键 词：水生呼肠孤病毒 基因组 进展 

分 类 号：S852.659.4[农业科学—基础兽医学]