胎羊体外循环与胎盘功能保护研究进展  

Advances in Research of Fetal Cardiac Bypass and Prevention of Placental Function

作　　者：钟慧[1] 陈张根[1] 

机构地区：[1]上海医科大学儿科医院心血管中心,上海200032

出　　处：《心血管病学进展》2000年第4期214-216,共3页Advances in Cardiovascular Diseases

摘　　要：Fetal cardiac operation has been done in sheep so a method to protect the fetal and placenta after cessation of bypass is important.This is to review the progress in research of fetal cardiac bypass and prevention of placental dysfunction.The placental dysfunction results from different factors such as distribution of blood flow,stress response,placental perfusion, hypothermia and higher pressure oxygen.Observations were made in fetal Cardiac Bypass.Administration of high dose of sodium nitropusside,the indomethacin,total spinal anesthetic to block the fetal stress response and the improvement the equipment of the cardiopulmonary bypass devices and the normotherimia with high flow can maintain the placental function.Currently informationindicates thatintrauterine correction of selected congenital cardiac defects will be available in human fetuses in notremote future.Fetal cardiac operation has been done in sheep so a method to protect the fetal and placenta after cessation of bypass is important.This is to review the progress in research of fetal cardiac bypass and prevention of placental dysfunction.The placental dysfunction results from different factors such as distribution of blood flow,stress response,placental perfusion, hypothermia and higher pressure oxygen.Observations were made in fetal Cardiac Bypass.Administration of high dose of sodium nitropusside,the indomethacin,total spinal anesthetic to block the fetal stress response and the improvement the equipment of the cardiopulmonary bypass devices and the normotherimia with high flow can maintain the placental function.Currently informationindicates thatintrauterine correction of selected congenital cardiac defects will be available in human fetuses in notremote future.

关 键 词：胎羊 体外循环 胎盘功能保护 研究进展 

分 类 号：R722.1[医药卫生—儿科]