肾脏病患者血清高密度脂蛋白及其亚组分变化  

CHANGES OF SERUM HIGH DENSITY LIPOPROTEIN AND ITS SUBTYPES IN RENAL DISEASE

作　　者：黄家麟[1] 李伟[1] 汪国良[1] 周黎明[2] 

机构地区：[1]安徽医科大学附属医院肾病内科 [2]安徽医科大学营养与食品卫生教研室

出　　处：《安徽医学》1991年第6期1-2,共2页Anhui Medical Journal

摘　　要：本文对正常人、未经治疗的肾病综合征和慢性肾功能不全患者血清脂质和高密度脂质白及其亚组分水平进行了研究。检测结果:肾病综合征组血清TC、TG、HDL-3C、LDL-C,TC/HDL-C明显高于正常组,HDL-C,HDL-2C明显低于正常组。慢性肾功能不全组血清TC、HDL-3C虽有升高,但无统计学意义。TG、LDL-C、TC/HDL-C明显高于正常组,HDL-C、HDL-2C明显低于正常组。以上表明,在不同肾功能状态,各组病人均有不同程度脂代谢异常。A serum level of high density lipoprotein (HDL) and its subtypes were studies in untreated patients of nephrotic syndrome (NS) and chronic renal insufficiency (CRI) as compared with that of normal healthy individuals. The results demonstrated that the serum TC, TG,HDL-3C,LDL-C and TC/HDL-Call denoted much higher in NS that that of normal group, yet HDL-C and HDL 2C markedly lower. CRI TC and HDL-3C were elevated but not signific-ant. TG, LDL-C and TC/HDL-C however werehigher and HDL-C, HDL-2C lower than normal individuals. These data suggested that in patiertts with different impairment of renal function would show different abnormal degree of lipid metabolim. The mechanism of such alterations and their clinical significance were discussed.

关 键 词：肾疾病 高密度脂蛋白 亚组分 

分 类 号：R692.04[医药卫生—泌尿科学]