甲状腺功能对急性心肌梗死患者预后及左心室功能的影响研究  

Effect of thyroid function on the prognosis of patients with acute myocardial infarction and left ventricular function

作　　者：蔡潮江[1] 王志龙[2] 

机构地区：[1]中国医科大学绍兴医院急诊科,浙江绍兴312030 [2]中国医科大学附属第一医院急诊科,辽宁沈阳110000

出　　处：《中国现代医生》2013年第2期1-3,6,共4页China Modern Doctor

基　　金：辽宁省科学技术计划立项课题(2008225009-20)

摘　　要：目的探讨甲状腺功能对急性心肌梗死患者预后及左心室功能的影响。方法选取笔者所在医院2009年6月～2011年6月收治的老年急性心肌梗死患者60例。对症治疗后,比较预后不良组与好转组的血清甲状腺激素水平及左心室功能情况。另外选择45例健康体检者作为对照组。结果与健康对照组比较,老年急性心肌梗死患者血清T4、T3、FT3含量降低,差异有统计学意义(P<0.05)。第3周和第5周末,预后不良组血清T4、T3和FT3明显低于好转组,两组比较差异有统计学意义(P<0.05)。血清FT4及TSH组间比较,差异无统计学意义(P均>0.05)。预后不良组LAD、LVDs和LVDd水平均明显高于好转组,两组比较差异有统计学意义(P<0.05)。预后不良组EF明显低于好转组,两组比较差异有统计学意义(P<0.05)。AMI患者不同心肌梗死部位的血清T4、T3水平比较差异无统计学意义(P>0.05)。结论监测血清甲状腺激素水平的变化对判断急性心肌梗死患者预后及左心室功能有一定意义。Objective To investigate the affect of thyroid function on the prognosis of patients with acute myocardial infarction and left ventricular function. Methods A total of 60 elderly patients with acute myocardial infarction of the author＇s hospital from June 2009 to June 2011 were selected. Serum thyroid hormone levels and left ventricular func- tion of poor prognosis group and improved group were compared after Symptomatic treatment. 45 healthy subjects were selected as the control group. Results Compared with the healthy control group, the serum T4, W3, FT3 of elderly pa- tients with acute myocardial infarction decreased. The difference was statistically significant （P 〈 0.05）. Serum T4, T3 and FT3 of the poor prognosis group were significantly lower than the improved group in the 3rd weeks and 5th week. The difference was statistically significant （P 〈 0.05）. The difference of serum FT4 and TSH between two groups was not statistically significant （P 〉 0.05）. LAD, LVDs, and LVDd of poor prognosis group were significantly higher than improved group. The difference was statistically significant （P 〈 0.05）. EF of the poor prognosis group was significantly lower than the improved group. The difference was statistically significant （P 〈 0.05）. Difference serum levels of T4, T3 of AMI patients with myocardial infarction was not statistically significant （P 〉 0.05）. Conclusion Monitoring the changes of serum thyroid hormone level has a certain sense in determining the prognosis of patients with acute myocardial infarction and left ventricular function.

关 键 词：甲状腺激素 急性心肌梗死 预后 左心室功能 

分 类 号：R541.4[医药卫生—心血管疾病]