超声辅助丙酮缩氨基脲的合成  

Synthesis of acetone semicarbazone under ultrasonic irradiation

作　　者：张玉全[1] 盖轲[1] 

机构地区：[1]陇东学院化学化工学院,甘肃庆阳745000

出　　处：《宝鸡文理学院学报（自然科学版）》2012年第4期33-35,共3页Journal of Baoji University of Arts and Sciences(Natural Science Edition)

基　　金：庆阳市科技局基金资助项目(G2011-15)

摘　　要：目的研究一种方便、快速合成丙酮缩氨基脲(AS)的方法。方法以盐酸氨基脲和丙酮为原料,室温下超声辐射协助合成丙酮缩氨基脲。考察原料配比、超声辐射频率和反应时间对反应产率的影响。结果在最佳反应条件下(nSHC∶nacetone=1∶10,超声频率59kHz,反应时间40min)合成了丙酮缩氨基脲,收率可达85%。结论此法与常规的加热反应法相比,反应时间短,产物收率高,操作简单。Aim To seek a convenient, rapid synthetic method of acetone semicarbazone（AS）. Methods Acetone semicarbazone is synthesized under ultrasonic irradiation at room condition by u- sing semicarbazide hydrochloride （SHC） and acetone as raw materials. The effect of reactants molar ratio, ultrasound irradiation frequency and reaction time on the yields of acetone semicarhazone syn- thesis is studied. Results Acetone semicarbazone is synthesized under the optimum synthetic condi- tions （molar ratio of semicarbazide hydrochloride to acetone is 1 ： 10 （nsnc ： n = 1 ： 10）, and the ultrasonic radiation frequency is 59 kHz, the irradiation time is 40 min）. The yield is over 85%. Con- clusion Compared with the conventional heating reactions, this method features shorter reaction time, higher product yields and easier operation.

关 键 词：超声波 丙酮缩氨基脲 盐酸氨基脲 

分 类 号：TQ241.33[化学工程—有机化工]