蛋白激酶C的活性改变对脊髓原代培养神经元突起生长影响的研究  

STUDY OF THE EFFECT OF CHANGE OF PKC ACTIVITY TO NEURITE OUTGROWTH OF PRIMARY CULTURAL NEURONS OF EMBRYONIC RAT SPINAL CORD

作　　者：杨萍[1] 殷玉芹[1] 李振强[1] 

机构地区：[1]第三军医大学解剖学教研室,重庆400038

出　　处：《神经解剖学杂志》2000年第2期143-146,共4页Chinese Journal of Neuroanatomy

基　　金：国家自然科学基金资助项目! ( No. 39570 373)

摘　　要：本实验利用神经细胞培养技术 ,在培养基中加入影响蛋白激酶 C活性的因素 ,用同位素和免疫组化方法观察蛋白激酶C总活性以及其亚型分布改变后大鼠脊髓原代培养神经元突起生长状态所发生的改变。结果表明 :蛋白激酶Using primary culture of neurons with addition of influential factors of PKC activity, the outgrowth change of the neurite of the primary cultural neurons after the change of PKC total activity and the distribution of subtypes of PKC was observed. The results showed the change of PKC activity was positively related with the neurite outgrowth. (Figures 1～14 on plate 25,26)

关 键 词：蛋白激酶C 神经突起 生长 脊髓原代培养 酶活 

分 类 号：R329[医药卫生—人体解剖和组织胚胎学]