骨折内固定术后感染的病原菌分析及防治措施  

Pathogens causing infections after internal fixation of fracture and prevention countermeasures

作　　者：施绒舟 胡奇哲 裘情密 

机构地区：[1]慈溪人民医院骨科,浙江慈溪315300

出　　处：《中华医院感染学杂志》2013年第1期71-72,131,共3页Chinese Journal of Nosocomiology

摘　　要：目的分析医院骨折内固定术后感染的危险因素,并提出防治措施,为临床治疗提供参考依据。方法采用回顾性调查方法对医院2146例内固定术后患者的临床资料进行分析,观察内固定术后感染病原菌的分布和耐药性。结果 2146例患者中发生感染102例,感染率4.75%;其中发生手术切口感染48例,感染率2.24%;不动杆菌属、铜绿假单胞菌、大肠埃希菌对头孢菌素等常见抗菌药物耐药率均较高,且存在相当严重的多药耐药现象。结论合理应用抗菌药物,慎用广谱抗菌药物,减少耐药菌株产生,及时公布细菌耐药性,做好药物不良反应监测,提高用药合理性。OBJECTIVE To analyze the risk factors for the infections after the internal fixation of fracture and propose the prevention countermeasures so as to provide reference for the clinical treatment. METHODS The clinical data of 2146 patients who underwent the internal fixation of fracture were retrospectively investigated,the distribution and drug resistance of the resistance were observed. RESULTS Of 2146 cases of patients investigated, the nosocomial infections occurred in 102 patients with the infection rate of 4. 75%, among which there were 48 patients with the surgical incision infections with the incidence rate of 2.24 %. Acinetobacter, Pseudornonas aerug- inosa and Escherichia coli were highly resistant to the common antibiotics such as cephalosporins and were seriously multidrug-resistant. CONCLUSION The reasonable use of antibiotics and the broad spectrum of antibiotics can reduce the drug resistant bacteria. It is effective to improve the rationality of medication to issue the bacterial resistance in a timely manner and monitor the adverse reactions of the antibiotics.

关 键 词：骨折 内固定术后感染 病原菌 

分 类 号：R181.32[医药卫生—流行病学]