抗菌药物临床应用的干预管理  

Interventions to clinical application of antibiotics

作　　者：史红[1] 宋剑[1] 张建明[1] 李志民[1] 史济经[1] 郑忠健 高金妹[1] 张国庆[1] 

机构地区：[1]上海市江湾医院医教科,上海200434

出　　处：《中华医院感染学杂志》2013年第1期150-151,共2页Chinese Journal of Nosocomiology

摘　　要：目的运用综合干预措施对临床使用抗菌药物进行管理。方法从2011年7月起进一步采取强化抗菌药物规范使用知识教育,执行住院患者抗菌药物使用率、使用强度、Ⅰ类切口抗菌药物信息化管理、制定特殊抗菌药物使用审批制度等干预措施,对干预前后住院患者的抗菌药物使用率、医院感染率等指标进行调查。结果除医院感染率无差异外,干预前后抗菌药物使用率由76.62%下降至68.91%、Ⅰ类切口抗菌药物使用率由93.18%下降至45.00%、抗菌药物使用强度由56.05DDD下降至51.46DDD,差异有统计学意义。结论运用综合干预措施对临床抗菌药物的使用进行管理,减少了抗菌药物不合理使用现象,提高了临床医师合理使用抗菌药物的自觉性。OBJECTIVE To use comprehensive interventions to the clinical application of antibacterial drugs. METHODS The knowledge education of the standardized used of antibiotics was further strengthened from Jul 2011, the information management of the utilization rate of antibiotics, intensity of use, antibiotics for type Ⅰ incision was implemented, the special approval system for antibiotics application was formulated. The utilization rates of antibiotics and the incidence of nosocomial infections before and after the interventions were investigated. RESULTS There was no difference in the incidence of nosocomial infections, the utilization rate decreased from 76.62% before the interventions to 68.91% after the interventions, the utilization rate of antibiotics for type Ⅰ incision decreased from 93. 18% to 45.00%, the antibiotics use intensity decreased from 56.05 DDD to 51.46 DDD, the differences were statistically significant. CONCLUSION The comprehensive interventions to the clinical application of antibiotics improves the clinicians＂ initiative of reasonable use of antibiotics.

关 键 词：抗菌药物 干预管理 研究 

分 类 号：R978.1[医药卫生—药品]