硝基乙醛肟及其盐的合成与表征  

Synthesis and characterization of methazonic acid and salts

作　　者：罗义芬[1] 王伯周[1] 张叶高[1] 霍欢[1] 贾思媛[1] 樊学忠[1] 

机构地区：[1]西安近代化学研究所,陕西西安710065

出　　处：《化学试剂》2013年第1期71-73,共3页Chemical Reagents

基　　金：国防基础科研计划资助项目(B0920110005)

摘　　要：以硝基甲烷为原料,在强碱溶液中反应得到硝基乙醛肟钠盐,再酸化得到硝基乙醛肟,收率75.5%,并采用红外光谱、核磁共振光谱、元素分析进行了结构表征;分析了反应历程,优化了反应条件,确定适宜反应条件为:n(CH3NO2)∶n(NaOH)为0.6∶1,反应时间20 min,反应温度50℃,溶液pH 1.5。利用硝基乙醛肟的酸性,设计并合成两种硝基乙醛肟衍生物。Methazonic acid was synthesized with a yield of 75.5% from nitromethane by acidifying sodium methazonate, which was prepared in the solution of sodium hydroxide, and its structure was confirmed by IR,1HNMR,13 CNMR and ele- mental analysis. The mechanism of the reaction was analyzed. The optimum conditions for the reactions were as follows：the mole ratio of CH3NO2 and NaOH was 0.6：1 ,the reaction time was 20 min,the reaction temperature was 50℃, and the pH of solution was 1.5. In addition, two salts of methazonic acid were designed and synthesized using its acidity.

关 键 词：有机合成 硝基乙醛肟 表征 

分 类 号：TJ55[兵器科学与技术—军事化学与烟火技术]