十二烷基胍盐酸盐的合成与性能  

Synthesis and Properties of Dodecylguanidine Hydrochloride

作　　者：宋永波[1] 李秋小[1] 李运玲[1] 智丽飞[1] 

机构地区：[1]中国日用化学工业研究院,山西太原030001

出　　处：《精细化工》2013年第1期28-31,共4页Fine Chemicals

基　　金：国家科技支撑计划项目(2012BAD32B10);山西省研究生创新项目(20113128)~~

摘　　要：以氰胺和十二烷基伯胺为原料,一步合成了十二烷基胍盐酸盐表面活性剂,经单因素实验确定了较佳工艺条件为:体积分数95%乙醇为溶剂,n(十二胺):n(氰胺):n(盐酸)=1:1.5:1.1,反应时间2 h。产品通过IR、1HNMR和元素分析进行了结构表征,并对其表面活性、泡沫性、乳化性和抑菌性进行了测试。结果表明,十二烷基胍盐酸盐的CMC为5.5 mmol/L,最低表面张力为24.1 mN/m,与DTAC相比,具有较好的泡沫性能,较差的乳化能力,较强的抑菌活性,在25 mg/L质量浓度下对金黄色葡萄球菌和大肠埃希氏菌的抑菌率达100%,在100 mg/L质量浓度下对白色念珠菌的抑菌率达99.5%。A cationic surfactant dodecylguanidine hydrochloride was synthesized and the optimized reaction conditions were ： n （dodecylamine） ： n （cyanamide） ： n （hydrochloride） = 1 ： 1.5 ： 1.1, refluxed for 2 h in ethyl alcohol solvent. The structure of the product was confirmed by IR, 1HNMR and elemental analysis. The properties of the product were measured, such as surface activity, foaming and emulsifying power,and antimicrobial capacity. The results showed that CMC of the product is 5.5 mmol/L, and TCMC is 24. 1 mN/m. The product had better foaming and lower emulsifying abilities than DTAC. The inhibition of cell viability for Staphylococcus aureus and Escherichia coli are 100% at the mass concentration of 25 mg/L and that for Candida albicans is 99.5% at the mass concentration of 100 mg/L respectively.

关 键 词：阳离子表面活性剂 十二烷基胍 性能 

分 类 号：TQ423.11[化学工程]