正交试验法优选软脉通瘀颗粒的醇提工艺  

Orthogonal Test the Alcohol Extraction Process of the Particles of the Soft Pulse Stasis

作　　者：谢燕[1] 李建利[1,2] 施明毅[1] 杨珊[1] 奚建[1] 王利洁[1] 

机构地区：[1]成都中医药大学药学院,四川成都611137 [2]四川省中医药科学院中医研究所,四川成都610031

出　　处：《亚太传统医药》2013年第1期26-28,共3页Asia-Pacific Traditional Medicine

基　　金：四川省科学技术厅项目(2010-4-295)

摘　　要：目的:优选软脉通瘀颗粒的醇提工艺。方法:以丹参酮ⅡA含量和醇提液干膏收率为考察指标,选取乙醇体积分数、溶剂用量、提取时间、提取次数为考察因素,采用正交试验优选丹参等醇提工艺。结果:最佳醇提工艺为用6倍量的70%乙醇,提取两次,每次1.5h。结论:应用该工艺提取效率高,合理,稳定可行,适合工业生产。Objective. Preferred alcohol extraction process of the particles of the soft pulse Stasis. Methods： A content and alcohol extract dry extract yield as the inspection index, the selection of ethanol volume fraction, solvent dosage, extraction time, extraction times in order to investigate factors, using the orthogonal experiment, optimizing salvia miltiorrhiza and alcohol extraction process. Results：The best ethanol--extraction process with 6 times for the amount of 70 % ethanol, extraction two times, each time 1.5h. Conclusion：The application of the extraction process is efficient, reasonable and practicable, suitable for industrial production.

关 键 词：软脉通瘀颗粒 正交试验 丹参酮ⅡA 醇提工艺 

分 类 号：R943[医药卫生—药剂学]