MCuⅡIUD与TCu380A IUD放置60个月临床效果对比研究  

A clinical study on 60 months of insertion of MCuⅡ functional IUD and TCu380A IUD

作　　者：赵艳晖[1] 武淑英[2] 王立岩[3] 李淑芝[4] 王玉[5] 

机构地区：[1]吉林大学第二医院妇产科,长春130041 [2]北京大学第三医院妇产科 [3]吉林大学中日联谊医院 [4]北京大学第一医院 [5]中国医科大学附属盛京医院

出　　处：《中国计划生育学杂志》2013年第1期25-28,共4页Chinese Journal of Family Planning

摘　　要：目的:观察放置MCuⅡ功能性宫内节育器(MCuⅡIUD)的临床效果及安全性。方法:国内多中心统一标准,选择2000例要求放置IUD避孕的妇女,随机放置MCuⅡIUD与TCu380A IUD各1000例,定期随访观察60个月。结果:放置满60个月,MCuⅡIUD与380ATCu IUD的带器妊娠率分别为1.83/百妇女年、2.10/百妇女年,差异无统计学意义(P>0.05);脱落率分别为0.72/百妇女年、3.03/百妇女年,差异有统计学意义(P<0.05);因出血/疼痛取出分别为4.54/百妇女年、6.12/百妇女年,副作用发生率分别为3.50%、3.80%,差异均无统计学意义(P>0.05);计划妊娠取器后两组妊娠率分别为86.6%、91.7%,差异无统计学意义(P>0.05)。结论:MCuⅡIUD避孕效应高,脱落率低,放置后出现副作用发生率低,可逆性好,是比较理想的IUD。Objective ： To study the clinical effect and safety of MCu Ⅱfunctional intrauterine contraceptive device （ MCu Ⅱ IUD）. Methods： A total of 2,000 women requiring IUD for contraception were recruited in a multicenter study. MCu Ⅱ IUD and TCu380A IUD were randomly inserted, 1,000 women each IUD. All women were regularly followed- up for 60 months. Results ： Sixty months after insertion, the rate of pregnancy with IUD in situ was 1.83/100 women per year in MCu II group and 2.10/100 women per year in TCu380A group, and the difference showed no statistical significance （P 〉 0.05 ）. The ex- pulsion rate in MCu Ⅱ group （0.72/100 women per year） was significantly lower than that in TCu380A group （3.03/100 women per year） （P 〈0.05）. The rate of IUD removal due to bleeding/pain was 4.54/100 and 6.12/100 women per year in MCu II group and TCu380A group, respectively, with no significant difference found （P 〉 0.05）. The rate of side effects was roughly the same in two groups （3.50% and 3.80%, respectively） （P 〉0.05）. The pregnancy rate after IUD removal for the reason of getting pregnant again was similar in MCu Ⅱ group （86.6%） and TCu380A group （91.7%） （P 〉 0.05）. Con- clusion ： MCu Ⅱ IUD is a comparatively ideal IUD, with good contraceptive effect, low expulsion rate, low occurrence of side effects after insertion, and good reversibility.

关 键 词：临床效果 多中心研究 MCuⅡIUD TCU380AIUD 

分 类 号：R169.4[医药卫生—公共卫生与预防医学]