巯基-β-环糊精/石墨烯复合膜电极对多巴胺的电化学行为研究  

A Study on Electrochemical Behaviors of Thiol-β-Cyclodextrine/Graphene Composite Film Modified Electrode for Dopamine

作　　者：龚霞[1] 马建国[2] 毛燕妮[2] 刘淑娟[2] 赵晓蕊[1] 熊友发[1] 

机构地区：[1]江西农业大学理学院,江西南昌330045 [2]东华理工大学化学生物与材料科学学院,江西抚州344000

出　　处：《江西农业大学学报》2012年第6期1291-1295,共5页Acta Agriculturae Universitatis Jiangxiensis

基　　金：江西省自然科学基金(2010GZH0011);江西省教育厅项目(GJJ11488)资助

摘　　要：利用β-环糊精的C(6)位羟基合成的巯基-β-环糊精(β-CD-SH)和石墨烯的混合物在金电极上制备复合修饰膜,用循环伏安法研究复合膜对多巴胺(DA)的电化学行为,实验结果表明,在pH=4.00的磷酸盐缓冲溶液中,氧化峰电流的变化与DA浓度在0.11～135μmol/L范围内呈良好线性关系,相关系数达0.991,检出限为1.1×10-7mol/L。用于模拟样品中DA的测定,回收率为98.2%～101.3%,效果较好。A derivative of thiol group of β-cyclodextrin（β-CD-SH） was synthesized via replacing C（6） hydroxyl group on β-cyclodextrin.Furthermore,a kind of new composite film modified gold electrode was prepared by β-CD-SH combined with graphene.Then its electrochemical behaviors towards the oxidation of dopamine（DA） were investigated.The results showed that the composite film modified electrode could reduce the oxidation overpotential of DA in pH=4.00 phosphate buffer solution（PBS）,the peak current of oxidation was proportional to the concentration of DA.and a good linear relation from 0.11～135 μmol/L（r=0.991） with a detection limit of 1.1×10-7 mol/L was obtained.When the method was applied to determining DA in simulated samples,a good recovery of 98.2%-101.3% was obtained.

关 键 词：巯基-β-环糊精 石墨烯 电化学行为 多巴胺 

分 类 号：TQ035[化学工程]