牛流行热病毒法国佐剂灭活疫苗的研制  

Inactivated Vaccine using French Adjuvant against Bovine Ephemeral Fever

作　　者：严隽端[1] 宋晓华[1] 黄金禄 彭新钢 白文彬[1] 

机构地区：[1]中国农业科学院哈尔滨兽医研究所,哈尔滨150001 [2]广州燕塘奶牛场,广州510230 [3]济南第二奶牛场,济南250002

出　　处：《中国预防兽医学报》2000年第4期267-270,共4页Chinese Journal of Preventive Veterinary Medicine

摘　　要：用法国赛比克公司提供的MontanideISA5 0佐剂和白油司盘佐剂配制的灭活疫苗对牛进行免疫试验 ,通过临床观察和血清中和抗体跟踪检测 ,结果表明 ,用MontanideISA5 0佐剂配制的疫苗在保持免疫效果的基础上 ,在降低疫苗接种反应上明显优于白油佐剂灭活苗 ,同时该疫苗在 4℃保存The immunity tests were proceeded with inactive Bovine Ephemeral Fever vaccines produced by two kinds of adjuvant:Montanide ISA50 adjuvant provided by French Sepic company and white oil adjuvant.Based on clinical observation and detection of serum neutralization test,the results show that the vaccine produced by Montanide ISA50 adjuvant surpasses the white oil adjuvant vaccine in the aspect of reducing the vaccinating reaction.It shows stable and good immunity after storage for four months at 4℃.

关 键 词：牛流行热 法国佐剂 灭活苗 免疫接种 

分 类 号：S858.235.3[农业科学—临床兽医学] S858.232.5[农业科学—兽医学]