不同生长年限及采收期牡丹皮中药效成分HPCE分析  

Research on the Content of Pharmacodynamic Components of Moutan Cortex by HPCE in Different Ages and Picking Periods

作　　者：胡煜雯[1] 巢建国[1] 谷巍[1] 刘训红[1] 孔昭琰[1] 

机构地区：[1]南京中医药大学药学院,江苏南京210023

出　　处：《南京中医药大学学报》2013年第1期63-65,共3页Journal of Nanjing University of Traditional Chinese Medicine

基　　金：江苏高校优势学科建设工程资助项目(ysxk-2010);江苏省中药炮制重点实验室开放课题(ZYPZ007);常州市科技支撑计划(农业)(CE20112019)

摘　　要：目的确立牡丹皮的最佳采收年限和最佳采收时期,为牡丹皮GAP生产提供依据。方法采用HPCE测定不同采收期牡丹皮中丹皮酚和没食子酸2种药效成分的含量。结果凤丹皮中药效成分的含量不同时期存在差异,不同年限中以5、6年生所含的丹皮酚和没食子酸含量相对较高;同一年份中各成分含量均在9、10月份达到相对高值且比较稳定。结论综合考虑各因素,牡丹皮以生长5年,在9、10月份为最佳采收时期。OBJECTIVE To determine the best harvesting time for Moutan Cortex and provide basis of GAP production. METHODS HPCE was employed to determine the content of 2 pharmacodynamic components（ paeonol and gallic acid） of Moutan Cortex at different ages and picking periods. RESULTS The contents of paeonol and gallic acid in Moutan Cortex were different in various harvesting time, and relatively higher in 5 or 6-year-old Moutan Cortex ; all components contents were high- er and more stable in September or October at the same harvesting year. CONCLUSION Concluding various factors, Septem- ber or October is the best harvesting time for 5-year-old Moutan Cortex.

关 键 词：牡丹皮 采收期 药效成分 HPCE 

分 类 号：R284.1[医药卫生—中药学]