前列腺动脉介入栓塞治疗前列腺增生症的临床评价  

Clinical evaluation of arterial embolizationin the treatment of benign prostatic hyperplasia

作　　者：邓健[1] 韩耕宇[1] 许卫国[1] 谢群[1] 

机构地区：[1]珠海市人民医院,广东珠海519000

出　　处：《现代泌尿外科杂志》2013年第1期60-62,共3页Journal of Modern Urology

基　　金：珠海市科技局课题(No.2009003)

摘　　要：目的探讨前列腺动脉介入栓塞治疗良性前列腺增生症的临床疗效。方法 2009年8月至2011年8月,选择确诊为前列腺增生、内科保守治疗无效、难以接受和不愿外科手术治疗的16例患者作为观察组,行放射介入法选择性前列腺动脉栓塞治疗。随机选择在我院行经尿道前列腺等离子电切术确诊前列腺增生的病例35例作为对照组。术后6个月随访。观察两组患者手术前后国际症状评分(IPSS)、生活质量评分(QOL)、最大尿流率(Qmax)、残余尿(RU)以及前列腺体积的变化。结果 16例接受PAE治疗的患者,IPSS由术前的(23.5±1.8)分降至术后的(13.1±1.7)分(P<0.05);QOL由术前的(4.7±0.5)分降至术后的(2.4±0.6)分(P<0.05);残余尿量由术前的(92.3±14.2)mL降至术后的(36.2±3.8)mL(P<0.05);Qmax由术前的(7.1±2.1)mL/s升至术后的(18.6±2.4)mL/s(P<0.05);前列腺体积由术前的(49.5±15.3)mL降至术后的(29.4±8.6)mL(P<0.05)。结论 PAE治疗前列腺增生安全、有效,且具有损伤小、出血少、手术风险低的优点,尤其适用于年老体弱、合并心肺并发症耐受力低下和拒绝接受外科治疗者,是前列腺电切术的有益补充。Objective To assess the clinical efficacy of prostatic arterial embolization （PAE） in treating benign prostatic hyperplasia （BPH）. Methods During Aug. 2009 to Aug. 2011, a total of 16 patients with BPH who failed medical treat- ment, or who were unable to tolerate or unwilling to accept surgery, were selected for PAE as the observation group. A total of 35 patients who had received plasma kinetic energy transurethral resection of the prostate （PKTURP） in the recent three yeas, who were followed up for 6 months, were analyzed retrospectively as the control group. The changes of indexes, such as International Prostate Score Symptom Score （IPSS）, Quality of Life （QOL）, peak urinary flow （Qmax）, residual urine （RU） preand post-treatment, were observed. Results For the 16 patients who underwent PAE, the IPSS decreased from 23.5±1.8 to 13.1 ±1. 7, QOL decreased from 4.7±0.5 to 2.4±0.6, RU decreased from （92.3±14.2） mL to （36.2 ± 3.8） mL, Qmax increased from （7.1± 2.1 ） mL/s to （ 18.6 ± 2.4） mL/s, the prostatic volume decreased from （49.5±15.3） mL to （29.4±8.6） mL （P〈0.05）. Oonclusion PAE is safe and effective to treat BPH, with the advantages of minimal invasion, little blood loss, and low risks. It is a feasible alternative option for patients BPH, especially for aged or weak patients who are unable to tolerate the operation, or unwilling to run the risks of PSTURP.

关 键 词：前列腺增生 前列腺动脉 介入栓塞 

分 类 号：R697[医药卫生—泌尿科学]