白细胞过滤器预防发热性非溶血性输血反应的临床观察及效果评价  

The Clinical Observation and Effect Evaluation of White Blood Cell Filter in the Prevention of Febrile Non-hemolytic Transfusion Reaction

作　　者：陈志远[1] 

机构地区：[1]内江市第二人民医院,内江641000

出　　处：《成都医学院学报》2012年第4期625-627,共3页Journal of Chengdu Medical College

基　　金：中国高校医学期刊临床专项资金(NO:11221622)

摘　　要：目的评估白细胞过滤器对于发热性非溶血性输血反应的临床疗效。方法将2010年9月～2011年12月的122例输血患者随机分为观察组与对照组,每组61例。观察组采用白细胞过滤器输血,对照组采用普通输血器输血,观察并比较两组发热性非溶血性输血反应的发生率。结果观察组患者体温平均差较低,FNHTR总发生率为9.84%;对照组FNHTR总发生率为27.87%,两组相比,差异有统计学意义(P<0.05)。表明白细胞过滤器能显著降低FNHTR发生率,在输血方面安全程度更高。此外,分别对比两组患者各频段FNHTR发生率可知,输血次数增加,FNHTR发生率升高,差异有统计学意义。结论白细胞过滤器可有效预防发热性非溶血性输血反应,提高了输血的安全性,尤其适用于需反复输血的患者,值得临床推广。Objective To investigate the clinical effect of white blood cell filter in the prevention of febrile non-hemolytic transfusion reaction. Methods 122 cases of transfusion patients in September 2010 to December 2011 were randomly divided into observation group and control group, with 61 cases in each group. The observation group was treated with leukocyte filter transfusion, while control group with common blood transfusion, the febrile nonhemolytic transfusion reaction rate was examined between the two groups. Results After surgery, the temperature change of the observation group was low, the incidence of FNHTR was 9.84%; the incidence of FNHTR was 27. 87 % in control group. There were significant differences in the two groups（P〈0.05）, which that the leukocyte filter can significantly reduce the incidence of FNHTR. In addition,the incidence rate of FNHTR in each band of the two groups was decreased, there were significant differences. Conclusion There are many merits in white cell filter, which can prevent the febrile non-hemolytic transfusion reaction, and improve the safety of blood transfusion, which was especially suitable for repeated blood transfusion patients. White blood cell filter is worthy of clinical application.

关 键 词：白细胞过滤器 输血反应 临床效果 

分 类 号：R457.13[医药卫生—治疗学]