血液C反应蛋白异常高值患者的病原菌感染调查  

Pathogens causing infections in patients with abnormally high value of blood C-reactive protein

作　　者：孙伟峰[1] 夏莉敏[1] 张健[1] 强新晨[1] 

机构地区：[1]南京医科大学附属无锡市人民医院检验科,江苏无锡214023

出　　处：《中华医院感染学杂志》2013年第2期320-322,共3页Chinese Journal of Nosocomiology

摘　　要：目的分析综合医院血液C反应蛋白异常高值患者病原菌感染部位分布及病原菌分布特点,为相关防治措施提供依据。方法对2011年1-10月符合条件的住院患者进行回顾性调查分析。结果来自279例患者的323份标本共分离出342株病原菌,痰液的检出率最高占44.6%,其次尿液占14.2%,血液占12.7%;检出的病原菌以革兰阴性菌为主占61.7%,革兰阳性菌占19.3%,真菌占19.0%;革兰阴性菌分别与革兰阳性菌、真菌相比较,其检出率差异均有统计学意义(P<0.01);革兰阴性菌主要为肺炎克雷伯菌、大肠埃希菌和鲍氏不动杆菌,分别占18.1%、15.5%、12.3%;革兰阳性菌主要为金黄色葡萄球菌、凝固酶阴性葡萄球菌,分别占7.6%、4.4%;真菌主要为白色假丝酵母菌,占16.1%。结论规范医务人员的技术操作,强化其控制医院感染意识,进行病原菌监测,对重点感染科室展开有效预防控制工作。OBJECTIVE To analyze the characteristics of distribution of the infection sites and pathogens in the patients with abnormally, high C-reactive protein in a genera hospital so as to provide basis for the prevention. METHODS The eligible hospitalized patients from Jan to Oct 2011 were retrospectively analyzed. RESULTS Totally 342 strains of pathogens were isolated from 323 specimens obtained from 279 patients,the sputum was the predominant specimens source （44.6 % ）, followed by the urine （14.2 % ） and the blood （12.7 % ） ; gram-negative bacteria were the main pathogens detected, accounting for 61.7%, gram-positive bacteria accounted for 19.3%, and fungi accounted for 19%; the difference in the detection rate between the gram-negative bacteria, gram- positive bacteria,and fungi was statistically significant （P〈0. 001） ; Klebsiella pneumoniae, Escherichia coli and Acinetobacter baumannii were the predominant gram-negative bacteria, accounting for 18. 1%, 15. 5%, and 12.3%, respectively; Staphylococcus aureus and coagulase-negative Staphylococci were the main gram-positive bacteria,accounting for 7. 6% and 4. 4%, respectively; Candida albicans was the major species of fungi, accounting for 16. 1%. CONCLUSION It is necessary to standardize the technical operation, intensify the awareness of infection control, monitor the pathogens, and carry out the effective prevention and control of infection in key departments.

关 键 词：C反应蛋白 感染 病原菌 患者 

分 类 号：R181.32[医药卫生—流行病学]