胸腺五肽对初治肺结核患者免疫功能和痰菌阴转率的影响  

作　　者：梁汉成 劳穗华[2] 

机构地区：[1]广东省东莞市慢性病防治院,523008 [2]广东省广州市胸科医院,510160

出　　处：《当代医学》2013年第3期140-141,共2页Contemporary Medicine

摘　　要：目的分析胸腺五肽对初治结核患者免疫功能以及痰菌阴转率的影响。方法选取2009年4月～2011年4月收治的阳性肺结核患者86例,按照随机抽取的方式划分为观察组和对照组,各43例,观察比较两组治疗前后免疫指标的变化和治疗后的痰菌阴转率。结果观察组1、2个月转阴率分别为74.4%、100%;对照组1、2个月转阴率分别为44.2%、90.7%,两组治疗后2个月内的阴转率比较差异有统计学意义(2=18.89,7.77,P<0.05)。结论胸腺五肽能够有效改善肺结核患者免疫功能,加速患者痰菌转阴进程,且无显著不良反应,整个临床治疗效果安全且可靠。Objective To study and analysis of thymic peptide five relative to the initial treatment of tuberculosis patients immune function and sputum conversion rate influence. Methods In our hospital from 2009 April to 2011 April were a total of 86 cases of pulmonary tuberculosis with positive, according to randomly divided into the observation group and the control group, 43 cases each, were compared between the two groups before and after treatment, the changes of immunological indexes and after treatment of sputum negative conversion rate. Results The observation group 1, 2 months of negative rates were 74.4%, 100%; control group 1, 2 months of negative rates were 44.2%, 90.7%, two group therapy 2 months after seroconversion rate had a significant difference （Z2=18.89, 7.77, P〈0.05）. Conclusion Thymic peptide five can effectively improve the immunologic function of patients with pulmonary tuberculosis, is accelerated in patients with sputum negative conversion process, and no obvious adverse reactions, the clinical therapeutic effect of safe and reliable.

关 键 词：胸腺五肽 结核 免疫功能 痰菌 

分 类 号：R521[医药卫生—内科学]