荭叶心通软胶囊中三七提取工艺研究  

Study on Extraction Process of Radix notoginseng in Hongyexintong Soft Capsule

作　　者：石凌云[1] 黄勇[1] 郑林[1] 王爱民[1] 王永林[1] 

机构地区：[1]贵阳医学院药学院,贵州贵阳550004

出　　处：《贵阳医学院学报》2012年第6期619-622,共4页Journal of Guiyang Medical College

基　　金：贵州省重大专项项目【黔科合重大专项字(2007)6010号】;贵州省科技计划项目(黔科合计工字[2009]4001号)

摘　　要：目的:优选荭叶心通软胶囊中三七药材的最佳提取工艺。方法:采用正交实验法,以人参皂苷Rg1、Rb1、三七皂苷R1的转移率为指标,优选三七的提取工艺。结果:最佳水煎煮工艺是加药材重量10倍的水(第一次多加2倍量),煎煮3次,每次1 h;最佳醇沉工艺是加乙醇使含醇量为55%,放置12 h。结论:优选的提取工艺对三七总皂苷提取率高,操作简便。Objective： To optimize the extraction technology process of Radix notoginseng in Hongyexintong soft capsule. Methods： The orthogonal test was employed for selecting the optimal ex- traction technology with transfer rates of ginsenoside Rgl, ginsenoside Rb1 and notoginsenoside R1 as indexes. Results： The optimal water extraction process was adding 10 fold water of medicinal material weight （ adding 2 fold more at the first time）, decocting 3 times and 1 h for each time. The optimal al- cohol precipitation technology was adding alcohol to concentration of 55% and laying 12 h. Conclu- sions： The optimized extraction process is easy and feasible with high extraction rate and provides a scientific basis for industrial production.

关 键 词：红蓼 制药工艺(中医) 三七 人参皂苷 

分 类 号：R9-39[医药卫生—药学]