破伤风抗毒素皮试液浓度及配制方法探讨  

Discussion on the Concentration and Preparation Method of Tetanus Antitoxin Skin Test Solution

作　　者：向虹宇[1] 母发旭[1] 汤小斌[1] 闵然星[1] 闫峻峰[1] 

机构地区：[1]四川省医学科学院/四川省人民医院药剂科,成都610072

出　　处：《中国药房》2013年第4期363-365,共3页China Pharmacy

摘　　要：目的:为降低破伤风抗毒素皮肤试验(以下简称"皮试")阳性率提供参考。方法:调查多家医院破伤风抗毒素的皮试液浓度和皮试液配制方法,结合相关权威资料和研究进展,分析目前临床破伤风抗毒素皮试液应用中存在的问题。结果与结论:破伤风抗毒素皮试阳性率过高,主要是由于皮试液浓度过高,溶媒选择不合理和注射器死腔造成药物吸取量增大等原因造成的,应在实际工作中加以注意。OBJECTIVE：To provide reference for the decrease the positive rate of tetanus antitoxin（TAT）skin test.METHODS：The status quo of the concentrations and preparation methods of tetanus antitoxin skin test solution in hospitals were investigated,and the existing problems were analyzed and explored on the basis of authoritative data and researches.RESULTS CONCLUSIONS：The major causes for high positive rate of TAT skin tests are the excessively high concentration of skin test solution,improper choices of solvent and the over withdrawal of liquor caused by the fixed volume of injectors,to which extra attentions should be paid in practice.

关 键 词：破伤风抗毒素 皮试液 浓度 配制 

分 类 号：R183[医药卫生—流行病学]