微通道反应器内叔丁醇溴化反应工艺研究  

RESEARCH ON BROMINATION OF tert-BUTYL ALCOHOL IN MICRO-CHANNEL REACTOR

作　　者：张跃[1] 郭欣桐[1] 严生虎[1] 刘建武[1] 沈介发[1] 

机构地区：[1]常州大学制药与生命科学学院,江苏常州213164

出　　处：《精细石油化工》2013年第1期58-62,共5页Speciality Petrochemicals

摘　　要：研究了微通道反应器中叔丁醇的溴化反应制备溴代叔丁烷的工艺过程,考察了原料摩尔配比、反应温度、催化剂浓硫酸的用量、停留时间等单因素对反应的影响。通过实验结果得到了较佳的工艺条件:反应温度为50℃,叔丁醇、氢溴酸和浓硫酸的摩尔比为1∶1.5∶1,停留时间60s,叔丁醇的转化率为92.3%,溴代叔丁烷的选择性为99.1%,传统间歇搅拌反应器中叔丁醇转化率为88.3%,溴代叔丁烷选择性为86.5%。相较于传统工艺方法,利用微通道技术提高了反应效果,降低了反应条件的要求,减少了废酸的产生,大大提高了生产效率。The preparation of tert-butyl bromide from tert-buthl alcohol through bromination reactionin the micro-channel reactor was presented. Effects as the molar ratio of two materials, the reaction temperature, the catalyst dosage and the resident time on bromination reaction were studied as well. The optimum conditions were obtained as follows., reaction temperature 50 ℃, the molar ratio of tert- butyl alcohol, hydrobromic acid and concentrated sulphuric acid 1 ： 1.5 ： 1, the resident time 60 s. The conversion of tert-butyl alcohol and the selectivity of tert-butyl bromide under these conditions were 92.3% and 99.1% respectively, while the corresponding results are 88.3% and 86.5% respec- tively when the reaction was carried out in the batch stirred tank reactor under the same conditions. Compared to the traditional process, the use of micro-channel technology can not only improve the el-

关 键 词：微通道反应器 叔丁醇 溴化 溴代叔丁烷 

分 类 号：TQ413.24[化学工程]