2009～2011云南省乙型病毒性肝炎患者血清学调查分析  

Epidemiology of hepatitis B virus from 2009 to 2011 in Yunnan province

作　　者：邵天波[1] 王卫红[2] 张秀玲[2] 邹大为[2] 杜艳[1] 陈瑞春[1] 许云敏[1] 

机构地区：[1]昆明医科大学第一附属医院,昆明650032 [2]昆明医科大学附属口腔医院

出　　处：《山东医药》2013年第1期15-17,共3页Shandong Medical Journal

基　　金：云南省科技厅-昆明医科大学应用基础研究联合专项(2011FB211);昆明医科大学大学生创新性实验计划项目(CX201125)

摘　　要：目的分析2009～2011年云南省乙型病毒性肝炎(乙肝)的感染状况,评价乙肝疫苗的预防效果。方法收集2009～2011年昆明医科大学第一附属医院门诊和住院患者的乙肝五项结果资料,用SPSS13.0统计分析软件按不同年龄段分析。结果共入选127 504例患者,HBsAg、anti-HBs、HBeAg、anti-HBe和anti-HBc总阳性率分别为7.0%、59.1%、1.5%、14.4%和26.8%,5岁以下儿童HBsAg阳性率为0.7%,这和中国国家疾控中心报道的结果吻合,基本达到国际标准。结论乙肝疫苗纳入云南省儿童计划免疫之后取得了显著的成效。Objective To determine the prevalence of hepatitis B virus in a representative population from 2009 to 2011 in Yunnan, in order to estimate the effect of immunization program. Methods From January 2009 to December 2011, a total of 127 504 in-/-out-hospital patients were studied. For all patients, blood samples were collected routinely and then hepatitis B surface antigen （HBsAg）, hepatitis B surface antibody （anti-HBs）, HBV e antigen （HBeAg）, HBV e antibody （anti-HBe） and hepatitis B core anti-body （anti-HBc） were tested and analyzed with SPSS version 13.0. Re- stilts The weighted prevalences of HBsAg, anti-HBs, HBeAg, anti-HBe and anti-HBc for the 127 504 patients were 7.0% , 59.1% , l. 5% , 14.4% and 26.8% , respectively, and the weighted prevalences of HBsAg was 0.7% among children less than 5 years, which was coincidence with the report from Chinese Center for Disease Control and Prevention. Conclusion Yunnan has already reached the national goal of reducing HBsAg prevalence to less than 1% among children less than 5 years, which shows that immunization program has gained a significant success.

关 键 词：正嗜肝DNA病毒属 流行 云南省 

分 类 号：R512.62[医药卫生—内科学]