急性高容量血液稀释用于神经外科手术患者的可行性与安全性  

Feasibility and security of acute hypervolemic hemodilution in neurosurgical patients

作　　者：巢少辉[1] 金建辉[1] 朱光彩[1] 毛剑[1] 

机构地区：[1]中国人民解放军第184医院神经外科,江西鹰潭335000

出　　处：《海南医学》2013年第2期181-183,共3页Hainan Medical Journal

摘　　要：目的探讨急性高容量血液稀释用于神经外科手术患者的可行性与安全性。方法将60例患者随机分成三组,分别为中分子羟乙基淀粉组、乳酸钠林格液组、聚明胶肽组,每组各20例。比较三组患者行AHH前后血液动力、肾功能、凝血功能情况。结果三组患者输液后30min CVP与AHH前比较有所上升,差异具有统计学意义(P<0.05)。三组患者输液后30min的Cr、BUN、β2-MG与AHH前比较均改变不大,差异无统计学意义(P>0.05)。三组患者输液后30min的PT、APTT与AHH前比较时间均上升,但差异无统计学意义(P>0.05)。结论急性高容量血液稀释是可靠的保护血液的方法,用于神经外科手术患者可行且安全。Objective To investigate the feasibility and security of acute hypervolemic hemodilution （AHH） in neurosurgical patients. Methods Sixty patients were randomly divided into three groups, Hydroxyethyl starch group, sodium lactate Ringer＇s solution group, polygeline group, each with 20 cases. The blood dynamics, renal func- tion, coagulation function before and after AHH were compared between the three groups. Results 30 min after Infu- sion, the CVP of three groups was significantly increased, compared with that before AHH （P〈0.05）. The levels of Cr, BUN, 132-MG showed no statistically significant difference with those before AHH （P〉0.05）. The PT, APTT time was slightly increased, with no statistically significant difference （P〉0.05）. Conclusion AHH is a method for the protec- tion of blood, which is feasible and safe for neurosurgical patients.

关 键 词：急性高容量血液稀释 神经外科 手术 可行性 安全性 

分 类 号：R651[医药卫生—外科学]