陶瓷膜过滤对连花清瘟胶囊水提液纯化工艺的影响  

Purification Process of Lianhua Qingwen Capsule Water Extraction with Ceramic Membrane Filtration

作　　者：刘敏彦[1] 张永锋[1] 史东霞[1] 许红辉[1] 李炳超[1] 李正杰[1] 范文成[1] 

机构地区：[1]石家庄以岭药业股份有限公司,河北石家庄050035

出　　处：《中国中医药信息杂志》2013年第1期64-66,共3页Chinese Journal of Information on Traditional Chinese Medicine

基　　金：国家科技重大专项-重大新药创制(2011ZX09201-201-27)

摘　　要：目的研究不同孔径无机陶瓷膜对中药连花清瘟胶囊水提液除杂效果及主要有效成分转移率的影响。方法以连花清瘟胶囊水提液为研究对象,采用8种不同孔径的无机陶瓷膜过滤,观察膜通量和主要有效成分的转移率。结果经过8种不同孔径陶瓷膜过滤后,连花清瘟胶囊水提液均较过滤前明显透明澄清,出膏率也有一定程度的下降,综合考虑实际生产因素,孔径为0.2μm的陶瓷膜管能保证在有效成分转移率和固形物去除率较高的条件下有较大的膜通量,适用于连花清瘟胶囊水提液除杂工艺。结论陶瓷膜过滤技术可有效改善连花清瘟胶囊水提液除杂的效果,可用于中药提取液精制生产领域。Objective To study the purification process and the retention rates of main active ingredients of Lianhua Qingwen Capsule water extraction with different pore size inorganic ceramic membrane.Methods Water extraction of Lianhua Qingwen Capsule was filtered by eight kinds of pore size inorganic ceramic membranes,the membrane flux and the retention rates of main active ingredients were observed.Results Water extraction liquid become clear and the cream rates decreased after filtered with ceramic membrane.Considering the actual production factors,the pore size of 0.2 μm ceramic membrane was selected to apply to purification process of Lianhua Qingwen Capsule water extraction,because of the higher retention rates of the active ingredients,the higher removal rates of impurities and the higher membrane flux.Conclusion Ceramic membrane filtration technology is effective to remove impurities of Lianhua Qingwen Capsule water extraction,and can be applied to the field of refining production of traditional Chinese medicine extraction.

关 键 词：连花清瘟胶囊 陶瓷膜过滤 纯化工艺 

分 类 号：R283.5[医药卫生—中药学]