上海市浦东新区美沙酮门诊吸毒人群HIV、HCV和梅毒感染状况分析  

The Analysis of Human Immunodeficiency Virus(HIV), Hepatitis C Virus(HCV) Infection and Syphilis Among the Drug Users at the Methadone Maintenance Clinic in Pudong District, Shanghai

作　　者：盛燕华[1] 汤琰[1] 王涛[1] 李旭[1] 马平[1] 朱林英[1] 

机构地区：[1]上海市浦东新区疾病预防控制中心,上海200136

出　　处：《中国初级卫生保健》2013年第1期74-76,共3页Chinese Primary Health Care

摘　　要：目的了解上海市浦东新区美沙酮门诊吸毒人群人类免疫缺陷病毒(HIV)、丙型肝炎病毒(HCV)和梅毒感染状况,为采取防治措施提供科学依据。方法采集浦东新区美沙酮维持治疗门诊吸毒人群静脉血标本共计833份,进行抗-HIV、抗-HCV和梅毒检测。结果 833名吸毒人员中,HIV抗体阳性0例;HCV抗体阳性602例,占72.27%(602/833);梅毒阳性38例,占4.56%(38/833)。HIV/HCV合并感染0例;梅毒/HCV合并感染24例,占2.86%(24/833)。结论上海市浦东新区2011年1月—2012年7月美沙酮门诊监测的吸毒人群中HIV感染率明显下降,HCV、梅毒感染率较高。建议应针对在美沙酮门诊治疗的吸毒人员感染情况开展多种疾病的宣传教育和综合干预,并继续在这部分人群中持续开展HIV、HCV和梅毒的监测工作。OBJECTIVE To survey the prevalence of human immunodeficiency virus（HIV）, hepatitis C virus（HCV） infection and syphilis among the drug users at the methadone maintenance clinic in Pudong District, Shanghai and provide scientific evidence for the development of appropriate prevention and control measures. METHODS A total of 833 blood samples were taken from these drug users to detect antibodies to HIV, HCV and syphilis. RESULT The positive rates of HIV, HCV and syphilis infections among the 833 drug users were 0, 72.27%（602/833） and 4.56%（38/833） respectively. The double positive rates of HIV＋ HCV and syphilis ＋ HCV were 0, 2.86% （24/833） respectively. CONCLUSION The infection rate of HIV declined obviously while the infection rates of HCV and syphilis were relatively higher among the drug users at the methadone maintenance clinics in Pudong District, Shanghai during January, 2011 to July, 2012. It is necessary to strengthen the targeted prevention, control measures, conduct constant HIV, HCV and syphilis surveillance among the drug users.

关 键 词：美沙酮 吸毒人群 HIV HCV 梅毒 

分 类 号：R512.91[医药卫生—内科学] R759.1[医药卫生—临床医学]