3.0T磁共振动态增强曲线与早期强化率对乳腺病变良恶性的鉴别诊断价值  

3.0 T magnetic resonance dynamic enhanced curve and early enhancement rate on the differential diagnosis value of benign and malignancy mammary gland disease

作　　者：赵桂娇[1] 付旷[1] 郭丽丽[1] 张肇慧[1] 赵明[1] 周丽[1] 曲溪倩[1] 

机构地区：[1]哈尔滨医科大学附属第二医院磁共振成像诊断科,黑龙江哈尔滨150086

出　　处：《中国实验诊断学》2013年第1期72-75,共4页Chinese Journal of Laboratory Diagnosis

摘　　要：目的探讨3.0T磁共振动态增强曲线类型与早期强化率对乳腺病变良恶性的鉴别诊断价值。方法对40例乳腺病变患者(均经病理证实)的MRI平扫及动态增强扫描影像学资料进行回顾分析。观察分析病变增强后血流动力学特点,包括时间—信号强度曲线(TIC)及96s、144s早期强化率。结果对乳腺病变良恶性的诊断:时间-信号强度曲线的灵敏度为0.842,特异度为0.762,AUC值(ROC工作曲线下面积)为0.8083;96s早期强化率(%)的灵敏度为0.526,特异度为0.857,AUC值为0.7193;144s早期强化率(%)的灵敏度为0.737,特异度为0.857,AUC值为0.8534。结论在诊断乳腺病变的良恶性方面,96s、144s早期强化率与时间-信号强度曲线类型三者相比:96s、144s早期强化率的特异度较高;时间-信号强度曲线类型的灵敏度较高;144s早期强化率的AUC最大,即144s早期强化率的诊断价值最佳。Objective To investigate the evaluation of 3.0 T magnetic resonance dynamic enhanced curve and early enhancement rate on the differential diagnosis value of benign and malignancy mammary gland lesions. Methods Plain MRI and dynamic contrast-enhanced scan imaging data were retrospectively analyzed 40 patients of breast lesions （a to tal of 40 cases were confirmed by pathology）. Observe and analyze lesions enhanced hemodynamic characteristics,inclu- ding time-signal intensity curve （TIC） and the 96s,144s early enhancement ratio. Results To diagnosis the benign and malignancy of breast lesions：The diagnosis sensitivity/ specificity/ the value of AUC （ROC area under the curve）/ of time-signal intensity curve patterns were 0. 842/0. 762/0. 8083;These of 96s early enhancement rate were0. 526 /0. 857/0. 7193 ;These of 144s early enhancement rate were 0. 737/ 0. 857/ 0. 8534. Conclusion In the diagnosis of benign and malignant breast lesions,compared among 96s, 144s early enhancement ratio and the time signal intensity curve type： the specificity of 96s/144s early enhancement rate is higher;the sensitivity of time signal strength curve type is higher; the AUC of 144 s early enhancement ratio is maximum,namely it has the best diagnostic value.

关 键 词：乳腺 动态增强 早期强化率 时间信号强度曲线 

分 类 号：R445.2[医药卫生—影像医学与核医学]