息风止痛颗粒对偏头痛模型大鼠的保护作用  

Protective Effect of Xifengzhitong GranμLe on Migraine Rats

作　　者：程静[1] 庞来祥[1] 李伟[1] 何建丽[1] 寻园[1] 

机构地区：[1]解放军第451医院中医药研究所,陕西西安710054

出　　处：《现代中药研究与实践》2012年第6期34-36,共3页Research and Practice on Chinese Medicines

摘　　要：目的研究息风止痛颗粒对偏头痛模型大鼠的保护作用。方法采用皮下注射硝酸甘油复制偏头痛模型,观察息风止痛颗粒对血清ET、His、NE、DA含量的影响。结果息风止痛颗粒能降低血清His含量,与模型组比较有显著性差异(P<0.05);降低DA含量趋势;升高NE、ET含量,与模型组比较有显著性差异(P<0.05)。结论息风止痛颗粒具有抗偏头痛的作用。Objective To study the protective effect of Xifengzhitong granμLe on migraine rats. Methods The model of migraine was set up by subcutaneous injection of nitroglycerin, and effects of Xifengzhitong granμLe on the serum of ET, His, NE, DA conten observed. ResμLts Xifengzhitong granμLe coμLd reduce serum His content significantly compared with model group （P 〈 0.05）, and reduce DA content trends and increase NE, ET content significantly compared with the model group. Conclusion Xifengzhitong granμLe showed anti- migraine effect.

关 键 词：息风止痛颗粒 偏头痛 

分 类 号：R285[医药卫生—中药学]