血脂的四联指数与急性心肌梗死的关系分析  

Relationship of acute myocardial infarction with serum lipid tetrad index

作　　者：李云慧[1] 李保强[1] 邱广斌[1] 

机构地区：[1]中国人民解放军第二〇二医院检验科,沈阳110003

出　　处：《国际检验医学杂志》2012年第18期2187-2188,共2页International Journal of Laboratory Medicine

基　　金：辽宁省科学技术计划资助项目(2011225021)

摘　　要：目的探讨急性心肌梗死(AMI)的发生与血脂四联指数(LTI)的相关性。方法选取77例AMI患者和61例健康体检人群为研究对象,测定三酰甘油(TG)、总胆固醇(TC)、脂蛋白(a)[Lp(a)]、高密度脂蛋白胆固醇(HDL-C)和低密度脂蛋白胆固醇(LDL-C)的含量。结果 AMI患者血清TG、TC、LDL-C、Lp(a)和LTI高于健康人(P<0.01),血清HDL-C低于健康人(P<0.01),差异均有统计学意义;血清LTI的ROC曲线下面积为0.962(95%CI 0.925～0.999),血清LTI预测AMI的灵敏度为90.9%,特异度为98.4%。结论血脂LTI可以作为预测AMI发生的重要指标。Objective The aim of this study is to assess the predictive value of lipid tetrad index for occurrence of acute myocar dial infarction. Methods A total of 77 patients with acute myocardial infarction and 61 healthy controls were recruited in this study. The routine parameters, triglyceride （ TG）, total cholesterol （TC）, low-density lipoprotein cholesterol （ LDL-C）, high-density lipoprotein cholesterol（HDLC）,and lipid （a）[Lp（a）] were measured. Results Serum levels of TG,TC,LDL-CLp（a） and LTI in AMI group were significantly higher than those in healthy controls （P〈0. 01） ,and serum level of HDL C was lower significantly than those in healthy controls （P〈0.01）. Receiver operating characteristic （ROC） curves of LTI were 0. 962（95%CI 0. 925- 0. 999）（P〈0.01）. LTI reached the highest sensitivity of 90. 9% and specificity of 98. 4%. Conclusion LTI may represent the helpful adjunct in the risk assessment for AMI.

关 键 词：心肌梗死 血脂异常 四联指数 

分 类 号：R542.22[医药卫生—心血管疾病]