武汉地区生殖道支原体体外耐药性分析  

In vitro drug resistance analysis of gential tract mycoplasma in Wuhan

作　　者：杨卫萍[1] 

机构地区：[1]武汉江汉大学附属医院检验科,湖北武汉430016

出　　处：《国际检验医学杂志》2012年第18期2213-2214,共2页International Journal of Laboratory Medicine

摘　　要：目的分析武汉地区生殖道支原体感染状况及药敏情况,为临床合理用药提供参考。方法对533例阴道分泌物标本进行支原体培养、鉴定及体外药敏试验检测。结果支原体培养总阳性率为72.98%,其中解脲脲原体阳性率为40.90%,耐药性由高到低依次为环丙沙星、氧氟沙星、红霉素、阿奇霉素、克拉霉素、四环霉素、交沙霉素、多西环素、原始霉素;人型支原体阳性率为2.06%,耐药性由高到低依次为红霉素、阿奇霉素、环丙沙星、克拉霉素、氧氟沙星、四环霉素、交沙霉素、多西环素、原始霉素;二者混合感染阳性率为30.02%,耐药性由高到低依次为环丙沙星、氧氟沙星、红霉素、克拉霉素、阿奇霉素、交沙霉素、四环素、原始霉素、多西环素。结论支原体耐药性在不同地区表现不同,临床应参照药敏试验结果合理选用抗菌药物。交沙霉素和多西环素是目前治疗武汉地区支原体感染的首选药物。Abstract：Objective To investigate the infection status and drug resistance of gential tract mycoplasma in Wuhan. Methods 533 cases of genital tract samples were detected for mycoplasma culture,identification and drug resistance. Results Total positive rate of mycoplasma was 72.98o/00. Positive rate of Ureaplasma urealyticum（Uu） was 40.90% ,and the drug resistances ranged from high to low were ciprofnkloxacin,ofloxacin,erythromycin,azithromycin,clarithromycin,tetracyckline,josamycin,doxycycline and pristinamycin. The positive rate of Mycoplasma hominis（Mh） was 2.06 %, and the drug resistances ranged from high to low were eryth- romycin,azithromycin, ciprofloxaein, clarithromycin, ofloxacin, tetracycline,josamycin, doxycycline and pristinamycin. The positive rate of mixed infection was 30.02 %,and the drug resistances ranged from high to low were ciprofloxacin,ofloxacin,erythromycin, clarithromycin, azithromycin,josamycin, tetracycline, pristinamycin and doxycycline. Conehlsion The drug resistance of mycoplas- ma might be different in vary areas. Josamycin and doxycycline could be used as the first choice for the treatment of mycoplasma in- fection in Wuhan.

关 键 词：女性泌尿生殖系统疾病 支原体 抗生素 抗药性 湖北 

分 类 号：R446.5[医药卫生—诊断学]