正交优选参斛颗粒水提组提取工艺研究  

Study on Extraction Process of Water Extract of Shenhu Granules by Orthogonal Experiment

作　　者：李煌[1] 谢伟容[1] 夏裕发[1] 褚克丹[1] 季国路[1] 施红[2] 张玉琴[1] 

机构地区：[1]福建中医药大学药学院,福建福州350122 [2]福建中医药大学中西医结合学院,福建福州350122

出　　处：《福建中医药大学学报》2012年第6期32-35,共4页Journal of Fujian College of Traditional Chinese Medicine

基　　金：福建省科技计划项目(2010Y2004);福建省高校服务海西重点建设项目(905000700)

摘　　要：目的筛选和优化参斛颗粒水提组的提取工艺。方法以丹酚酸B含量、多糖含量及固形物量为考察指标,采用正交实验设优选参斛颗粒剂的水提工艺。结果最佳工艺为丹参、五味子醇提后的药渣和方中其他药物水提,采用12倍量水,提取2次,每次1 h。结论用正交法优选参斛颗粒剂的提取工艺稳定、可行。Objective To study the optimized extraction process of water extract of Shenhu granules. Methods The contents of salvianolic acids B, polysaccharide and dry extract from the drug were chosed as the index, and the optimum conditions were investigated by orthogonal test. Results The optimized extraction process was 10 folds amount ofwater, 2 times, one hours. Conclusion The optimized extraction process is scientific and efficient.

关 键 词：参斛颗粒剂 正交实验 提取工艺 

分 类 号：TQ461[化学工程—制药化工]