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机构地区:[1]泸州医学院附属医院乳腺外科,四川泸州646000
出 处:《泸州医学院学报》2012年第6期625-626,共2页Journal of Luzhou Medical College
摘 要:目的:评价粗针穿刺活检在乳腺癌诊断中的价值。方法:对2011至2012年我院可疑乳腺癌患者301例术前进行粗针穿刺活检,所取组织石蜡切片病理检查。结果:301名可疑乳腺癌患者中,病例诊断为乳腺癌236例,术后病检均证实为乳腺癌,与粗针结果相一致,阴性65例(包括可疑病例15例),其中可疑15例中术后病检均证实为乳腺癌12例。其特异性100%,灵敏度95.16%,阳性预测值100%,阴性预测值81.53%,假阳性率0%。术后并发症:乳腺局部血肿20人,经局部加压包扎处理,血肿均缓解,无感染及种植转移、血道转移病例。结论:粗针穿刺操作简单,术后并发症少,在乳腺癌的诊断及指导治疗方面可广泛应用。Objective: To evaluate the application of coarse needle biopsy in diagnosis of breast cancer.Methods: Biopsy with large sized needle was used in 301 patients with suspected breast cancer.The obtained tissues were processed into wax slices for pathological examination.Results: Among 301 cases of suspected breast cancer,236 cases were positive,pathologically diagnosed as breast cancer,which were further confirmed by post-operative pathology.65 cases were negative,but among them,12 cases had breast cancer verified by postoperative pathology.Statistical analysis indicated that specificity was 100%,sensitivity 95.16%,positively prospective value 100%,negatively prospective value 81.53%,and pseudo positivity 0%.Post-puncture complications included local hematoma 20 cases;all were relieved with pressure bandage.No infection,no metastasis via implantation or blood flow was found.Conclusion: Puncture with large sized needle is simple,with few complications,which may be widely used in diagnosis and instructive therapy of breast cancer.
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