椎体后凸成形术治疗骨质疏松性椎体骨折的随访分析  

Retrospective analysis of osteoporotic vertebral fractures treated with kyphoplasty

作　　者：王根林[1] 杨惠林[1] 孟斌[1] 郑召民[2] 张宁[3] 殷国勇[3] 梅昕[1] 周军 朱雪松[1] 汪李军[1] 

机构地区：[1]苏州大学附属第一医院骨科,江苏苏州215006 [2]中山大学附属第一医院骨科,广东广州510080 [3]南京医科大学第一附属医院骨科,江苏南京210029

出　　处：《苏州大学学报（医学版）》2012年第6期865-867,共3页Suzhou University Journal of Medical Science

基　　金：国家自然科学基金资助项目(81271960;81171689;81071451);卫生行业科研专项基金资助项目(201002018)

摘　　要：目的回顾性研究经皮椎体后凸成形术(KP)治疗骨质疏松性椎体骨折的疗效。方法回顾性分析2000年5月至2012年10月行KP治疗且资料较完整的1 459例骨质疏松性椎体骨折患者的临床资料,从腰背部疼痛(VAS评分)改善率、常见并发症发生率及生存率三方面评价手术疗效。结果平均随访51个月(1～92个月),VAS评分术前为8.7±1.0,末次随访为2.5±0.9,差异有统计学意义(P<0.05),VAS改善率为71.3%;骨水泥渗漏率2.4%;随访4年以上生存率75.3%。结论 KP治疗骨质疏松性椎体骨折能有效缓解患者疼痛,并发症低,安全有效。Objective To study retrospectively the efficacy of osteoporotic vertebral fractures （OVF） treated with percutaneous kyphoplasty （KP）. Methods The clinical data of I 459 patients with OVF were analyzed retrospectively from May 2000 to October 2012. The outcomes of KP for OVF were assessed by the improving rate of visual analogue scale （VAS） , the rate of common complications and the survival rate. Results The mean follow-up was 51 months （ ranged from one to 92 months）. The VAS was 8.7 ± 1.0 at preoperative and 2.5 ± 0.9 at final follow-up. There was statistically significant improvement at the final follow-up assessment compared with the pre-operative assessment （ P 〈 0.05 ）, VAS improved rate was 71.3%. The rate of cement leakage was 2.4% and the survival rate of up to four years was 75.3%. Conclusion The study suggests that kyphoplasty is a safe and effective procedure for OVF.

关 键 词：椎体后凸成形术 骨质疏松症 椎体压缩骨折 温度梯度灌注法 骨水泥 

分 类 号：R683.205[医药卫生—骨科学]