二维斑点追踪显像技术评价成人房间隔缺损左室功能的初步研究  

Assessment of left ventricle regional function by two dimensional speckle tracking imaging in patients with atrial septal defects

作　　者：楼玉美[1] 马小欣[1] 陈亚娣[1] 沈文均[1] 葛世俊[1] 周建庆[1] 郑哲岚[2] 

机构地区：[1]宁波市医疗中心李惠利医院,宁波315000 [2]浙江大学医学院附属第一医院

出　　处：《现代实用医学》2012年第12期1333-1336,共4页Modern Practical Medicine

摘　　要：目的探讨二维斑点追踪显像技术(2D-STI)对房间隔缺损(ASD)未行矫正患者左室局部功能的诊断价值。方法分别对35例继发孔型房缺患者和25例正常组在心尖四腔切面取连续5个心动周期的动态图像,存盘后用脱机软件QLab中的TMQA功能测得左室游离壁各节段的纵向应变和应变率数据(结合心电图及计算得到最大应变/应变率,平均收缩期应变/应变率及平均舒张期应变/应变率)。结果应变:ASD组左室游离壁中间段及心尖段显著高于正常组(<0.05),但基底段仅平均舒张期应变高于正常组(=0.014)。应变率:两组差异有统计学意义,ASD组左室游离壁各节段的最大应变率、平均收缩期应变率、平均舒张期应变率均普遍高于正常组,但基底段平均舒张期应变率与正常组差异无统计学意义(=0.812)。结论 2D-STI是一种无创评价左室局部功能的有效手段。Objective To assess the diagnostic value of two dimensional speckle tracking imaging（2D-STI）on left ventricle（LV） regional function in patients of uncorrected atrial septal defect（ASD）.Methods Thirty-five patients of uncorrected ASD[26F/9M,aged（41.71±16.17）years ] were enrolled as the ASD group,and 25 healthy adults [16F/9M,aged（44.50±12.11）year）] were as the control group.Live images of consecutive five heart cycles in apical four-chamber were acquired and dates of strain and strain rate were analyzed by QLab Software.Results Strains of LV segments in middle and apical wall were higher than those of the control group（ 0.05）,but strain of LV segments in basal wall did not differ significantly,only higher in mean diastolic strain,compared with the control group（=0.014）.The maximum strain rate,mean systolic strain rate and the mean diastolic strain rate of ASD group LV free wall segment were generally higher than those of the control group,but mean diastolic strain rate in LV basal lateral wall did not differ significantly from the control group（=0.812）.Conclusions 2D-STI is a non-invasive evaluation of LV regional function.

关 键 词：房间隔缺损 超声心动描记术 心室功能 左 二维斑点追踪显像技术 

分 类 号：R541[医药卫生—心血管疾病] R445.1[医药卫生—内科学]