模拟输电环境电磁场对动物血清和细胞超微结构的影响  

Effect of Electromagnetic Fields in Simulated Transmission Environment on Animal Serum and Cell Ultrastructure

作　　者：耿读艳[1] 徐桂芝[1] 万晓伟[1] 邢凌霄[2] 谢红娟[1] 

机构地区：[1]河北工业大学河北省电磁场与电器可靠性省部共建重点实验室,天津300130 [2]河北医科大学,石家庄050017

出　　处：《高电压技术》2013年第1期163-174,共12页High Voltage Engineering

基　　金：河北省自然科学基金(E2012202012)~~

摘　　要：为研究交流高压输电线路产生的低频环境电磁场对人体的生物效应,采用哺乳动物在体实验研究了具有椭圆极化场源特征的模拟电磁环境对动物血清和细胞超微结构的影响。血清生化分析显示,当实验动物经过Ⅰ区域电磁场(3.5～4.5kV/m、40～48μT)曝露后,谷草转氨酶(ALT)、谷丙转氨酶(AST)和尿素氮(BUN)含量明显升高,肝细胞凋亡率明显增加。当实验动物经过Ⅱ区域电磁场(2.3～3.5kV/m、48～50μT)曝露后,上述指标未产生具有统计学意义的变化。由细胞超微结构的电镜观察结果可知,2种实验参数均使得细胞线粒体的大部分嵴和膜出现轻中度融合。研究结果表明,低强度低频电磁场(2～5kV/m,20～60μT,50Hz)曝露可能会影响动物的肝、肾功能,并能通过某种途径诱导细胞线粒体超微结构发生异常。In order to explore the biological effect of low frequency environmental electromagnetic fields（EMF） produced by high voltage AC transmission lines on human body,in vivo experiments on mammals were performed.Using simulated electromagnetic environment with elliptically polarized characteristic,we investigated the effects of EMF on animal serum and cell ultrastructure.The biochemical analyses of animal serum indicate that the contents of aspartate aminotransferase（ALT）,alanine aminotransferase（AST）,and blood urea nitrogen（BUN） remarkably increase after exposing the experimental animals to EMF Ⅰ（3.5-4.5 kV/m,40-48 μT）,and the cell apoptosis rate in liver increases significantly.However,no statistically changes in these indexes are found in experimental animals that are exposed to EMF Ⅱ（2.3-3.5 kV/m,48-50 μT）.According to electron microscopic observation results of ultrastructure,two sets of experimental parameters cause mild or moderate fusion of mitochondrial cristae.It is concluded that the exposure of low intensity and low frequency EMF（2-5 kV/m,20-60 μT,50 Hz） may influence the function of mammalian liver and renal,and can induce ultrastructural abnormalities of mitochondria by some means.

关 键 词：高压输电线 环境电磁场 生物效应 在体实验 动物血清 超微结构 电磁场曝露 

分 类 号：Q64[生物学—生物物理学]