2型糖尿病住院患者糖化血红蛋白与果糖胺及空腹血糖的相关分析  

Correlation of HbA1c level. with fasting plasma glucose and fructosamine in type 2 diabetic inpatients

作　　者：田小平[1] 徐宁[2] 尹冬[2] 陈新宽[1] 庄惠芹[1] 苏彩女[1] 

机构地区：[1]连云港市第一人民医院检验科,222002 [2]连云港市第一人民医院内分泌科,222002

出　　处：《中国糖尿病杂志》2013年第1期63-65,共3页Chinese Journal of Diabetes

摘　　要：目的分析住院T2DM患者HbA1c水平与FPG和果糖胺(FRU)之间的相关性。方法选取432例住院T2DM患者,按HbA1c水平分为<6.5%、6.5%～7.5%和>7.5%3组。分析各组HbA1c与FPG、FRU之间的相关性。结果 HbA1c<6.5%组,HbA1c与FPG和FRU之间无相关性(r=0.254,P=0.108;r=-0.032,P=0.884),TG与HbA1c呈正相关(r=0.342,P=0.031);6.5%～7.5%组,HbA1c与FPG和FRU之间无相关性(r=0.153,P=0.151;r=0.167,P=0.132),WHR与HbA1c呈正相关(r=0.230,P=0.035);>7.5%组,HbA1c与FPG和FRU呈正相关(r=0.522,P=0.000;r=0.770,P=0.000)。各年龄段患者(<65岁,65～80岁,>80岁)HbA1c与FPG和FRU之间均呈正相关(r=0.2193～0.2921,P<0.01;r=0.6525～0.7436,P<0.01)。结论住院的HbA1c<7.5%的T2DM患者,FPG、FRU与HbA1c水平无相关性,三指标间的一致性较差。Objective To analyse the correlation of HbA1 c levels with FPG and fructosamine（FRU） in type 2 diabetic inpatients Methods The 432 cases of type 2 diabetic inpatients were divided into HbAlc 〈6,5%, 6.5%-7.5% andS7. 5% groups according to their HbAlc levels. The correlation of HbA1 c levels with FPG and FRU was analyzed Results In the HbA1 c 〈6. 5 % group, the HbA1 c lev- els had no significant correlation with FPG and FRU （r= O. 254, P= 0. 108 ; r：=0. 032, P= 0. 884）, and TG was positively associated with HbA1 c（r： 0. 342, P： 0. 031）. In the HbA1 c 6.5 %- 7.5 % group, the H bA1 c levels had no significant correlation with FPG and FRU （r = 0. 153, P = 0. 151~r： 0. 167, P 0. 132）, and WHR was positively associated with HbAlc （r： 0. 230, P ~ 0. 035）. In the HbA1 c：〉 7.5 % group, the HbA~ c levels was positively correlaed with FPG and FRU（r= 0. 522, P= 0. 000;r=0. 770, P： 0. 000）. In all age groups（age^65 years, 65~80 years, and ~80 years）, the HbAlc level was positively correlated with FPG and FRU （r=0. 2193-0. 2921,P〈0. 01;r：0. 6525,0. 7436, P〈0. 01）. Conclusion The HbA1 c level has no significant relation with FPG and FRU in type 2 diabetic inpatients with HbAI c 7. 5%. There is a poor consistency in the correlation of HbA1 c with FPG and FRU.

关 键 词：糖尿病 2型 糖化血红蛋白 果糖胺 空腹血糖 

分 类 号：R587.1[医药卫生—内分泌]