45例莫西沙星不良反应病例分析  

Analysis of 45 Cases of ADR Induced by Moxifloxacin

作　　者：邬丹莲[1] 陈志高[1] 窦文琴[1] 陈婷婷[1] 

机构地区：[1]东南大学医学院附属江阴人民医院药剂科,江苏江阴214400

出　　处：《中国药物警戒》2013年第1期42-43,共2页Chinese Journal of Pharmacovigilance

摘　　要：目的探讨莫西沙星不良反应的一般规律和特点,为减少不良反应发生率及临床合理用药提供参考。方法对2009年至2011年我院的45例莫西沙星不良反应按照性别、年龄、给药途径等方法进行统计与分析。结果近3年我院莫西沙星不良反应逐年增加,2011年增加量尤为明显,其中新的严重的不良反应所占比例增加,皮肤黏膜类不良反应所占比例升高且女性不良反应发生例数显著增加,年龄因素对莫西沙星不良反应的影响每年基本相似。结论临床应重视莫西沙星的不良反应,特别注意皮肤黏膜不良反应的发生,及早做好应对措施。Objective To investigate the general rules and characteristics of moxifloxacin＇s adverse reaction, so as to provide advice for reducing adverse reaction rate. Method We analysed the moxifloxacin＇s adverse reaction from 45 inpatients during 2009-2011. Result The number of moxifloxacin＇s adverse reaction has increased year by year during recent three years, especially 2011. Meanwhile, the percentage of the new and serious ADR, the cutaneous and mucosa ADR and the woman ADR was significantly increased. Conclusion The doctors need to pay attention to moxifloxacin＇s adverse reaction, especially skin and mucosa ADR.

关 键 词：莫西沙星 药品不良反应 皮肤黏膜 性别 

分 类 号：R978[医药卫生—药品] R994.11[医药卫生—药学]