心脏再同步化治疗无应答的一些新认识  

New Opinions on Non-response to Cardiac Resynchronization Therapy

作　　者：王涛[1] 夏云龙[1] 

机构地区：[1]大连医科大学附属第一医院心内科,辽宁大连116011

出　　处：《心血管病学进展》2013年第1期115-117,共3页Advances in Cardiovascular Diseases

基　　金：国家自然科学基金(30800378);项目名称:心力衰竭发生恶性室性心律失常的三维单向动作电位研究资助

摘　　要：心脏再同步化治疗在终末期心力衰竭治疗中的地位日益重要。新近的欧洲指南中心脏再同步化治疗植入的适应证不断扩大。但有20%～30%的患者在安装了心脏再同步化治疗之后,效果不明显,称为心脏再同步化治疗无应答。合理地定义心脏再同步化治疗的应答,应该更注重患者症状和改善,而不片面追求临床指标的改善。关注新的预测心脏再同步化治疗有应答的方法,选择最优的预测方法,如QRS波时限等预测方法,预测心脏再同步化治疗植入效果,将加深对心脏再同步化治疗无应答的认识,降低心脏再同步化治疗无应答率,使更多的心力衰竭患者受益。Cardiac resynehronization therapy （CRT） plays an import role in the therapy for terminal heart failure. In the latest Euro- pean guidelines for heart failure therapy, the use of CRT implantation has gradually increased. However, 20% -30% of patients with CRT show no obvious effects after CRT; this is called non-response. In order to improve patient response to CRT, more methods need to be found that can foreeast the efficacy of CRT for individual patients. The current optimal method for predicting which patients will respond to CRT is the duration of the QRS wave in heart failure. However, more options are needed in order to further improve patient response rate to CRT.

关 键 词：心力衰竭 心脏再同步化治疗 无应答 

分 类 号：R541.6[医药卫生—心血管疾病]