无创正压通气治疗COPD并呼吸衰竭的临床疗效  

作　　者：李正兴[1] 蒋国强[1] 

机构地区：[1]四川省中江县人民医院呼吸科,618100

出　　处：《当代医学》2013年第5期11-12,共2页Contemporary Medicine

摘　　要：目的探讨无创正压通气治疗慢性阻塞性肺疾病并发呼吸衰竭的临床效果。方法选取四川省中江县人民医院2008年8月～2012年8月收治的慢性阻塞性肺疾病并发呼吸衰竭患者68例,随机分为观察组和对照组,各34例。对照组患者给予常规治疗,观察组在此基础上给予无创正压通气治疗,观察两组治疗前后的临床疗效。结果治疗后,观察组的总有效率为94.12%(32/34),显著高于对照组79.41%(27/34),P<0.05;治疗后治疗组的动脉血氧分压(PaO2)显著高于对照组,动脉血二氧化碳分压(PaCO2)显著低于对照组,每分的呼吸次数和心率均显著低于对照组,差异均有统计学意义(均P<0.05)。结论采用无创正压通气治疗慢性阻塞性肺疾病并发呼吸衰竭能显著提高临床有效率,使PaO2、PaCO2、呼吸频率和心率趋于正常水平。Objective To investigate the clinical effects of noninvasive positive pressure ventilation in the treatment of chronic obstructive pulmonary disease complicated by respiratory failure. Methods 68 cases of chronic obstructive pulmonary disease patients with respiratory failure in our hospital from August 2008 to August 2012 were chosen as the research object. They were randomly divided into the observation group and the control group, and each group was of 34 cases. The control group was received conventional therapy, and the observation group was given with non-invasive positive pressure ventilation on the basis of the control group. The clinical efficacy of the two groups before and after treatment were observed. Results After treatment, the total effective rate of the observation group was 94.12% （32 cases）, significantly higher than that in the control group of 79.41% （27 cases） （P〈0.05）. The PaO2 in the treatment group was significantly higher than the observation group, and PaCO2 was significantly lower than the control group, the breathing frequency and heart rate were significantly lower than the control group, P 〈0.05. Conclusion The application of noninvasive positive pressure ventilation in the treatment of chronic obstructive pulmonary disease with respiratory failure can significantly improve clinical efficiency, and make the respiratory rate and heart rate of PaO2, PaCO2 tend to normal levels.

关 键 词：无创正压通气 慢性阻塞性肺疾病 呼吸衰竭 

分 类 号：R563.9[医药卫生—呼吸系统]