389例子宫内膜异位症患者中医证候分布规律研究  

Regularity of TCM Syndrome Distribution in 389 Patients with Endometriosis

作　　者：钱静[1] 王劲松[1] 胡秀明[1] 王静莲[1] 仇颖琰[1] 于文娟[1] 

机构地区：[1]扬州大学医学院,江苏扬州225001

出　　处：《中华中医药学刊》2013年第1期7-9,共3页Chinese Archives of Traditional Chinese Medicine

基　　金：江苏省社会发展基金资助项目(BS2007039)

摘　　要：目的:根据子宫内膜异位症患者的临床症状及体征,分析证候分布规律,探讨其病因病机。方法:收集389例子宫内膜异位症患者的临床资料,采用因子分析和聚类分析研究。结果:一类共有表征信息的相关因子为气滞血瘀,并提取3个相关公因子,分别为寒凝、湿热、肾虚,389例患者经聚类分析形成3种证候:寒凝气滞血瘀证45.2%(176/389),湿热气滞血瘀证20.0%(78/389)和肾虚气滞血瘀证34.70%(135/389)。结论:内异症的症状和体征信息经多元统计分析可得出1个共性特征和3个常见证候,气滞血瘀反映本病的基本病机和基础证候,寒凝、湿热、肾虚反映本病不同个体,不同阶段病理状态和临床表现,为临床辨证分型提供依据。Objective：According to clinical symptoms and signs on endometriosis（EMs） patients,to analyze syndrome distribution regularity and discussing etiology and pathogenesis on EMs.Methods：Clinical data on 389 EMs patients were analyzed by factor analysis and cluster analysis.Results：Qi stagnation and blood stasis are correlation factors in common,and extracted three related factors（cold coagulation,damp- heat,kidney asthenia） respectively,389 EMs patients were assigned to three groups by cluster analysis：cold coagulation and qi stagnation and blood stasis syndrome was 45.2%（176/389）, damp-heat and qi stagnation and blood stasis syndrome was 20%（78/389） and kidney deficiency and qi stagnation and blood stasis was 34.70%（135/389）.Conclusion：By multivariate statistical analysis,EMs symptoms and signs can be drawn from a common features and three common syndromes.Qi stagnation and blood stasis reflects the basic pathogenesis and Zhenghou.Cold coagulation,damp-heat and kidney asthenia reflect the different stages of disease,pathology and clinical manifestations with different individuals,and can be taken as objective indexes for syndrome typing of Ems.

关 键 词：子宫内膜异位症 中医证候分布 中医病因病机 因子分析 聚类分析 

分 类 号：R711.71[医药卫生—妇产科学]