益气化瘀解毒方含药血清对鸡胚尿囊膜血管生成的影响  

Study on Influence of Prescription of Strengthening Qi and Resolving Stasis and Eliminating Toxin on Serum Chicken Embryos Allantoic Membrane Angiogenesis

作　　者：郜文辉[1] 曾普华[2] 潘敏求[2] 唐珍[1] 

机构地区：[1]湖南中医药大学中医学院,湖南长沙410006 [2]国家中医药管理局重点学科,湖南省中医药研究院附属医院肿瘤科,湖南长沙410006

出　　处：《中华中医药学刊》2013年第1期19-20,I0002,共3页Chinese Archives of Traditional Chinese Medicine

基　　金：国家自然科学基金资助项目(81001522);首届中国中西医结合学会-金港榄香烯中医药肿瘤研究基金资助项目(2010-F10)

摘　　要：目的:探讨益气化瘀解毒含药血清对鸡胚尿囊膜血管生成的影响。方法:取孵育7 d的种蛋制成CAM模型,加入益气化瘀解毒整方高、中、低3个剂量组的含药血清,继续孵育3 d,固定标本,拍熙,计数新生毛细血管数目。结果:高、中、低剂量组与不合药血清组比较,差异均有统计学意义(P<0.05);高、中剂量组与低剂量组比较,差异均有统计学意义(P<0.05);高、中剂量组间比较,差异无统计学意义(P>0.05)结论:益气化瘀解毒方能抑制CAM血管新生,具有抗血管生成作用。Objective：To study the influence of prescription of strengthening Qi and resolving stasis and eliminating toxin on serum chicken embryos allantoic membrane angiogenesis.Methods：Eggs incubated for 7d were made into CAM model Joined high,medium and low doses of the serum containing medicine,and they were continuely to incubate for 3d. The specimens were fixed,took pictures,and the number of new blood capillary was counted.Results：The high,medium and low dose groups and no medicine group comparison differences were statistically significant（P0.05）.High,medium and low dose groups comparison were statistically significant（P0.05）.High,medium between dose groups comparison had no significant difference（P0.05）.Conclusion：The prescription of strengthening Qi and resolving stasis and eliminating toxin can inhibit CAM angiogenesis,and has the antiangiogenic effect.

关 键 词：益气化瘀解毒方 鸡胚尿囊膜 血管生成 

分 类 号：R285.5[医药卫生—中药学]