GC-MS分析不同产地天仙子及其炮制品中的脂肪酸成分  

Analysis of Fatty Oil in Seed of Hyoscyamus niger in Various Habitats and Its Processed Samples with GC-MS

作　　者：王秀琴[1] 李军 李岚 门启鸣 康廷国[4] 

机构地区：[1]沈阳市苏家屯区中医医院,辽宁沈阳110101 [2]大连市食品药品检验所,辽宁大连116021 [3]大连民大中药饮片有限公司,辽宁大连116600 [4]辽宁中医药大学,辽宁大连116600

出　　处：《中华中医药学刊》2013年第1期166-168,共3页Chinese Archives of Traditional Chinese Medicine

基　　金：大连市科技局基金资助项目(2009J22DW039);辽宁省"百千万人才工程"培养经费资助项目(201112)

摘　　要：目的:分析天仙子脂肪酸中成分组成,比较炮制对其脂肪酸组成的影响,比较不同产地天仙子脂肪酸组成。方法:GC-MS方法分析天仙子中脂肪酸组成,用气相色谱面积归一化法测定了各成分的相对百分含量。结果:经毛细管色谱分离并鉴定出11个峰。亚油酸含量最高(65.36%),其次是油酸(14.59%),还有肉豆蔻酸(4.85%)、棕榈酸(4.63%)、硬脂酸(2.58%)、α-亚麻酸(14.59%)、山嵛酸(0.55%)等。首次采用GC对不同产地及不同炮制品中脂肪酸成分进行了比较分析。结论:3个产地的天仙子中脂肪酸组成变化不明显。炮制后部分脂肪酸组成成分相对百分含量增加或减少,未见成分组成的质变。Objective：To analyze the compositions of fatty oil in the seeds of Hyoscyamus niger L.;To investigate the influence of processing on the compositions of fatty oil in the seeds;To compare the differences of the compositions of the fatty oil in the seeds from various habitats.Methods：GC-MS was used to analyze the compositions of the fatty oil in the seeds.Results：11 compositions were isolated and identified,including linoleic acid（65.36%）,oleic acid（14.59%）,myristic acid（4.85%）,palmitic acid（4.63%）,stearic acid（2.58%）,α- linolenic acid（14.59%）,behenic acid （0.55%）,and etc.It is firstly reported that the compositions of the fatty oil in the seeds from various habitats and the processed samples were studied comparatively.Conclusion：There was no significant difference in the fatty oil of the seeds from the three regions.The relative content of some compositions increase or decrease after the seeds were processed.

关 键 词：天仙子 脂肪酸 炮制 GC-MS 

分 类 号：R284.3[医药卫生—中药学]