Sysmex CA1500全自动血凝仪纤维蛋白原两种测定方法的应用比较  

Evaluation of two different methods of fibrinogen assay by the automatic coagulometer of Sysmex CA1500

作　　者：冯彩莲 康志君 李诗韵 黄瑜璇 

机构地区：[1]广东省广州市新海医院,510300

出　　处：《检验医学与临床》2013年第1期43-44,共2页Laboratory Medicine and Clinic

摘　　要：目的对Sysmex CA1500全自动血凝仪纤维蛋白原测定方法 Von Clauss法和PT-der法的应用进行比较评价。方法对门诊及住院患者167例标本同时用Von Clauss法和PT-der法测定,将结果按PT-der法测定的纤维蛋白原(FIB)含量分为3个水平组进行比较,并进行统计学分析。结果对PT-der法与Von Clauss法测定FIB含量进行比较,当FIB浓度在2.0～4.0g/L时,两组结果差异无统计学意义(P>0.05)。当FIB>4.0g/L或<2.0g/L时,差异有统计学意义(P<0.05)。结论 Von Clauss法准确性高,特异性强,快速简便,但试剂昂贵,而PT-der法不需另行独立测定,可节约试剂成本。实验室可将两种方法结合,这样既能保证结果的准确性,又保证检测速度,提高工作效率,节约成本。Objective To evalute two different methods of fibrinogen assay by the automatic coagulometer of Sysmex CA1500.Methods Von Clauss method and PT-der method were used to detect 167 clinical samples.FIB was divided into 3 groups based on the results of PT-der method.The result of FIB was analyzed by statistical method.Results Compare with two methods of PT-der and Von Clauss,there was not statistically significant difference（P0.05） when the concentration of fibrinogen was between 2.0-4.0 g/L.When the concentration of fibrinogen was lower than 2.0 g/L or higher than 4.0 g/L,the two methods had statistically significant difference（P0.05）.Conclusion Von Clauss has high veracity,it is a fast and simple method,but the reagent is very expansive.PT-der method don＇t any reagent,so the cost is low.The combination of the two methods can make sure that works are good quality and rapid,improve efficiency,and reduce the reagent cost.

关 键 词：全自动血凝仪 纤维蛋白原 Von CLAUSS法 PT-DER法 

分 类 号：R446.113[医药卫生—诊断学]