肝硬化自发性腹膜炎腹水的病原菌及耐药性探讨  

Pathogen and drug resistance exploration of cirrhosis ascites with spontaneous peritonitis

作　　者：杨玉贵[1] 

机构地区：[1]郑州市第六人民医院肝病三科,河南郑州450015

出　　处：《中国当代医药》2013年第2期195-196,共2页China Modern Medicine

摘　　要：目的分析肝硬化自发性腹膜炎腹水的病原菌及耐药性。方法回顾性分析本院收治的70例肝硬化自发性细菌性腹膜炎腹水患者的临床资料,对腹水细菌培养结果及药物敏感性结果进行分析。结果在本组资料中,革兰阴性杆菌52例,占74.3%,大肠埃希菌32例,占45.7%,革兰阳性菌对万古霉素比较敏感,革兰阴性菌对亚胺培南和阿米卡星敏感性较高,对其他抗生素敏感性较差。结论肝硬化自发性腹膜炎腹水要尽早进行腹水培养,结合临床症状,根据药敏结果合理选择抗生素。Objective To analyze the pathogens of cirrhosis ascites with spontaneous peritonitis （CASP） and the situations of their drug resistance. Methods Clinical data of 70 patients with CASP admitted into our hospital were retrospectively analyzed as well as the outcomes of ascites bacteria cultivation and drug sensitivity. Results Among these data, 52 cases were related to the gram-negative bacilli, accounted for 74.3% and 32 cases were due to the escherichia coli, accounted for 45.7%. The gram-positive bacilli were sensitive to vancomycin, whereas the gram-negative bacilli were more sensitive to imipenem and amikacin in comparison with other antibiotics. Conclusion The ascites bacteria cultivation should be implemented for those patients with CASP as soon as possible. Together with clinical signs and symptoms, based on the outcomes of drug sensitivity test, physicians can rationally select some antibiotics in treatment.

关 键 词：肝硬化 腹膜炎 腹水 病原菌 药敏试验 

分 类 号：R657.31[医药卫生—外科学]