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作 者:肖静[1] 杨梅[1] 李小杉[1] 韩磊[2] 高月霞[1]
机构地区:[1]南通大学公共卫生学院流行病与卫生统计教研室,江苏省南通市226019 [2]江苏省疾病预防控制中心职业病防治所
出 处:《职业与健康》2013年第1期32-35,共4页Occupation and Health
基 金:国家自然科学青年基金资助项目(项目编号:31000539);江苏省重点实验室开放课题(项目编号:K10003)
摘 要:目的探讨代谢综合征(MS)与脂肪肝的相关性,为采取有效的防治措施提供科学依据。方法采用SPSS 18.0统计软件:对不同年龄、工龄、性别和地区的10 437例江苏省电力从业人员健康检查数据中的MS与脂肪肝检出率进行分析,比较脂肪肝组和非脂肪肝组肥胖、高血压、高血糖和血脂紊乱发生率的优势比(OR),多因素逐步logistic回归分析脂肪肝的危险因素。结果 10 437例健康检查人群中MS和脂肪肝的检出率分别为5.49%、29.80%;MS与脂肪肝的检出率随年龄、工龄增加而增加,且男性的检出率均高于女性(P<0.01);除血脂紊乱和肥胖外,苏北地区的各项检出率均高于苏南和苏中两组;与非脂肪肝组相比,脂肪肝组肥胖、高血压、高血糖、血脂紊乱和MS检出率的OR为1.26,3.76,3.75,6.46,15.41,脂肪肝是MS的一个重要的危险因素;Logistic回归分析显示,脂肪肝与甘油三酯(TC)、血清总胆固醇(TG)、高血压及空腹血糖(FPG)有密切关系。结论 MS与脂肪肝的关系密切,脂肪肝患者具有MS各组分聚集的特征,应加强对职工健康理念及生活习惯的干预,预防脂肪肝与MS的发生。[Objective]To investigate the correlation between metabolic syndrome(MS) and fatty liver,provide scientific basis for implementing effective control measures.[Methods]Using SPSS18.0 statistical analysis software,the detectable rates of MS and fatty liver from health examination data of 10 437 employees with different age,length of service,gender and region in electric power enterprises in Jiangsu Province were analyzed,the odds ratio(OR) of incidence rate of obesity,hypertension,hyperglycemia and dyslipidemia in the fatty liver group and non-fatty liver group was compared,and the risk factors of fatty liver were analyzed by multiple factor stepwise logistic regression.[Results]The detectable rate of the MS and fatty liver among the 10437 health examination cases was 5.49% and 29.80% respectively,which increased with increasing age and length of service,and the detectable rates in males were higher than those in females(P0.01).Except dyslipidemia and obesity,the detectable rates of other indexes in Northern Jiangsu were higher than those in Southern Jiangsu and the middle region of Jiangsu.Compared with the non-fatty liver group,OR value in detectable rates of obesity,hypertension,hyperglycemia,dyslipidemia and MS in fatty liver group was 1.26,3.76,3.75,6.46,15.41,respectively,which indicated that fatty liver was an important risk factor of MS.Logistic regression analysis showed that fatty liver had close relationship with TC,TG,hypertension and FPG.[Conclusion]MS has a close relationship with fatty liver.The patients with fatty liver has the characteristic of various MS components gathering together,so it is necessary to strengthen the intervention of health concept and lifestyle among employees to prevent the fatty liver and MS.
关 键 词:代谢综合征 脂肪肝 LOGISTIC回归分析
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