2006—2011年汉中市麻疹疑似病例lgM抗体检测结果  

Detection results of IgM antibody among suspected measles cases in Hanzhong City from 2006-2011

作　　者：高洁[1] 赵汉民[1] 李姝霖[1] 韩亦非[1] 

机构地区：[1]陕西省汉中市疾病预防控制中心检验科,723000

出　　处：《职业与健康》2013年第1期88-89,共2页Occupation and Health

摘　　要：目的通过对2006—2011年麻疹疑似病例lgM抗体检测结果分析,了解汉中市麻疹流行特征及趋势,为制定控制和消除麻疹策略和措施提供科学依据。方法采用酶联免疫捕获法对汉中市11县区疾病预控制中心送检的麻疹疑似病例血清标本进行lgM抗体检测。结果共检测标本490份,麻疹lgM抗体阳性278份,阳性率为56.73%;各年份间和各年龄组间的阳性率差异有统计学意义(P<0.05)。麻疹的发病数逐年下降。对64份麻疹lgM抗体阴性标本进行风疹lgM抗体测定,阳性率为45.31%。麻疹在3—6月份高发,4月份为发病高峰。不同免疫史间麻疹lgM抗体的阳性率差异有统计学意义(P<0.05)。结论应加强对成人的强化免疫。加强免疫规划精细化管理,及时查漏补种,提高接种质量,做好疫情监测。对风疹的预防控制不容忽视。[Objective]To analyze the detection results of IgM antibody among suspected measles cases from 2006-2011,understand the epidemiological characteristics and trend of measles in Hanzhong City,and provide the scientific evidence for making the strategies and measures of measles control and elimination.[Methods]IgM antibody in serum samples of suspected measles cases submitted by Centers for Disease Control and Prevention in 11 counties of Hanzhong City was detected by capture enzyme immunoassay.[Results]Among 490 samples,278 were positive for IgM antibody to measles with the positive rate of 56.73%,and there were significant differences in the positive rate between different age groups and years（P0.05）.The number of measles cases decreased year by year.64 samples which were negative for measles antibody were detected for the antibody to rubella,and the positive rate was 45.31%.The incidence of measles was high during March to June,and hit the peak in April.The difference in positive rate of measles antibody between people with different immune history was significant（P0.05）.[Conclusion]It is necessary to strengthen the supplementary immunization among adults,reinforce elaborate management of immune programming,carry out revaccination in time,improve the quality of vaccination,and implement the monitoring of the epidemic situation.The prevention and control of rubella must not be ignored.

关 键 词：麻疹 风疹 疑似病例 lgM抗体 

分 类 号：R181.8[医药卫生—流行病学]