血液灌流在重度有机磷农药中毒治疗中的应用研究  

Application study of hemoperfusion in the treatment of severe organophosphorus pesticide poisoning

作　　者：何震宇[1] 王钟芳[1] 王玉梅[1] 

机构地区：[1]山东省威海市文登中心医院重症医学科,264400

出　　处：《临床合理用药杂志》2013年第2期18-19,共2页Chinese Journal of Clinical Rational Drug Use

摘　　要：目的探讨血液灌流(HP)在重度有机磷农药中毒中的作用。方法收集该院重度有机磷农药中毒患者87例,观察患者昏迷清醒时间、胆碱酯酶恢复时间及机械通气时间。结果各组昏迷清醒时间、胆碱酯酶恢复时间及机械通气时间比较差异均有统计学意义(P<0.05)。结论在常规治疗基础上行HP治疗重度有机磷农药中毒,患者昏迷清醒时间、胆碱酯酶恢复时间及机械通气时间均明显缩短,且越早进行HP治疗受益越早。Objective To discuss the role of hemoperfusion （HP） in the treatment of severe organophosphorus pesticide poisoning.Methods 87 cases of patients with severe organophosphorus pesticide poisoning in our hospital were collected.The coma recovery time、cholinesterase recovery time and mechanical ventilation time of all the patients were observed.Results There were statistical differences in the coma recovery time,cholinesterase recovery time and mechanical ventilation time among the groups （P0.05）.Conclusion The patients with organophosphorus pesticide poisoning were given HP treatment on the basis of conventional therapy,the coma recovery time,cholinesterase recovery time and mechanical ventilation time of them were significantly shorter.And the earlier treatment with HP,the sooner benefit.

关 键 词：中毒 有机磷农药 重度 血液灌流 昏迷清醒时间 胆碱酯酶恢复时间 机械通气时间 

分 类 号：R595.4[医药卫生—内科学]