面积应变评价正常人左心室收缩模式及功能  

Evaluation of left ventricular contraction pattern and function with area strain

作　　者：姚静[1] 许迪[1] 戴阳[1] 张艳娟[1] 谢冰[1] 李相权[1] 

机构地区：[1]南京医科大学第一附属医院心脏科,南京210029

出　　处：《中华超声影像学杂志》2013年第1期1-5,共5页Chinese Journal of Ultrasonography

基　　金：国家自然科学基金（81000618）;江苏省属高校自然科学研究基金（10KJD320001）;江苏高校优势学科建设工程资助项目（JX10231801）

摘　　要：目的应用四维应变（4D strain）技术分析正常人左室17节段收缩期面积应变峰值及达峰时序分布规律，探讨其临床应用价值。方法健康志愿者31例，采集左室实时三维全容积动态图像，应用EchoPAC分析软件测量左室容积及功能参数，以及各节段及整体收缩期面积应变峰值及应变达峰时间，分析面积应变参数在左室各节段的分布规律及节段参数在检查者间、检查者内的差异，以及左室整体面积应变峰值与射血分数的相关性。结果下壁基底段、左室心尖部收缩期面积应变峰值较小；左心室下壁、后室间隔、前室间隔基底段应变达峰时间较早；节段面积应变参数重复性较好；左室整体面积应变峰值与射血分数呈负相关（r=-0．688，P=0．000）。结论四维应变技术测量的面积应变参数可用于定量分析左心室心肌收缩模式及左室收缩功能。Objective To evaluate left ventricular （LV） myocardial contraction patterns and function by analyzing the distribution of peak value of segmental area strain and time sequence to the peak value.Methods 31 healthy subjects were involved. Real-time three dimensional full volume images of LV were acquired and analyzed with EchoPAC. LV volume and function parameters, as well as segmental and global systolic area strain and time to peak value were measured. The distribution of peak segmental area strain and time sequence to the peak value, interobserver and intraobserver variability of area strain parameters, as well as the relationship between global area strain and ejection fraction were evaluated. Results The peak segmental area strain was lower in the basic inferior and apical segments, and the peak value was reached earlier in the basic inferior, anteroseptal, and septal segments. Intraobserver and interobserver reliability of area strain parameters were good. Furthermore, a negative correlation was observed between global area strain and ejection fraction （ r = - 0. 688, P = 0. 000）. Conclusions The area strain measured by 4D strain can be used to evaluate the LV myocardial motion pattern and function.

关 键 词：超声心动描记术 心室功能 左 面积应变 

分 类 号：R445.1[医药卫生—影像医学与核医学]