1389例剖宫产预防用抗菌药物的使用分析  

Analysis on Preventive Use of Antibacterials in Cesarean Section on 1 389 Cases

作　　者：文晓丽[1] 史涛[1] 

机构地区：[1]中国人民解放军第174医院,福建厦门361002

出　　处：《中国药业》2013年第2期55-57,共3页China Pharmaceuticals

摘　　要：目的分析医院剖宫产预防用抗菌药物使用情况,以利合理用药。方法查阅2010年6月至2011年12月,产科剖宫产1 389份电子病例,对其中预防性抗菌药物使用情况进行回顾性调查分析。结果1 389例剖宫产手术抗菌药物使用率达100%。术前2 h内用药661例(47.59%),术后0～3 h用药475例(34.20%)。术后预防性用药持续给药时间3 d内1 046例(75.31%),大于3 d的有343例(24.69%)。抗菌药物单用1 174例(84.52%),二联用药208例(14.97%),三联用药7例(0.50%);以单用为主,主要使用头孢菌素类。结论医院产科抗菌药物预防性用药基本合理,但仍需按照抗菌药物使用原则应用,确保临床用药安全、经济、合理和有效。Objective To analyze the application situation of antibacterials in the patients with cesarean section in our hospital to facili- tate rational drug use. Methods 1 389 electronic medical records of cesarean section in the obstetrics department from Jun. 2010 to Dee. 2011 were consulted and the preventive use situations of antibacterials were performed the retrospective investigation and analy- sis. Results Among 1 389 cases of cesarean section,the use rate of antibaeterials was 100%. 661 eases（47.59% ） received antibacteri- al medication at preoperative 2 b,475 cases（34.20% ） at postoperative 0-3 h. 1 046 cases （75.31%） received antibacterial medica- tion for consecutive 3 d and 343 cases （24.69%） for more than 3 d. 1 174 cases （84.52%） received single antibacterial agent and 208 cases（14.97% ） received two-drug combination use and 7 cases （0. 50% ） received 3-drug combination use. The single drug use was predominant. The most widely used kinds were cephalosporins. Conclusion The preventive use of antibacterials in the obstetric de- partment is basically rational. But antibacterial agents still need to be used according to the antibacterial agents application principle for ensuring the safety,economy,rationality and efficiency in clinical medication.

关 键 词：剖宫产 抗菌药物 合理用药 

分 类 号：R969.3[医药卫生—药理学] R978[医药卫生—药学]