手足口病导致脱甲症的回顾性调查分析  

Retrospective study on onychomadesis linked to hand,foot and mouth disease.

作　　者：肖新才[1] 陈纯[1] 丁鹏[1] 王荀[2] 甘立勤[2] 王鸣[1] 

机构地区：[1]广州市疾病预防控制中心,广东广州510440 [2]中山大学公共卫生学院,广东广州510080

出　　处：《中国儿童保健杂志》2013年第2期201-204,共4页Chinese Journal of Child Health Care

摘　　要：【目的】了解广州市手足口病患者脱甲症发生情况,为临床诊治提供参考。【方法】采用统一设计调查表,以电话调查、家庭随访等的方式调查患者家长,调查内容包括患儿一般情况,手足口病病史以及脱甲症发生情况三个方面。【结果】356名手足口病实验室确诊病例中发现脱甲症患者14例,罹患率3.93%,其中85.71%为其他肠道病毒感染者,平均年龄29个月,脱甲发生时间距离手足口病发病期平均30.71d,平均脱甲为7.35个手指(脚趾)。【结论】广州市儿童手足口病患者愈后存在罹患脱甲症现象,多发于其他肠道病毒感染引起手足口病患者,脱甲症是否为手足口病的一种远期并发症有待深入研究。[Objective] To explore the attack rate of onychomadesis linked to hand,foot and mouth disease in Guangzhou. [Method] All lab-confirmed HFMD cases were follow up by home visit and telephone survey. [Rerults] 14 of the 356 HFMD cases had been attack by onychomadesis,attack rate were 3.93%, 85. 71%of them were HFMD cases caused by other enterovirus infections （non EV71 and non CoxA16）,the average number of shed nails was 735 per case, HFMD in these 14 cases had started an average of 34 days before onset of onychomadeses and the changes on the nail. [Conelusions] Onychomadesis may occurred after HFMD, and most caused by other enterovirus infections. Further research are need to demonstrate whether or not onychomadesis is a long-term complication of HFMD.

关 键 词：手足口病 脱甲症 肠道病毒 

分 类 号：R725[医药卫生—儿科]